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Optimized conditions for gene transduction into primary immune cells using viral vectors

Chimeric antigen receptor (CAR) T cell therapy has emerged as a promising modality for anti-cancer treatment. Its efficacy is quite remarkable in hematological tumors. Owing to their excellent clinical results, gene- modified cell therapies, including T cells, natural killer (NK) cells, and macropha...

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Detalles Bibliográficos
Autores principales: Kim, Yeongrin, Lee, Da Yeon, Choi, Ji U, Park, Jin Song, Lee, So Myoung, Kang, Chung Hyo, Park, Chi Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390464/
https://www.ncbi.nlm.nih.gov/pubmed/37524755
http://dx.doi.org/10.1038/s41598-023-39597-2