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DISC-3D: dual-hydrogel system enhances optical imaging and enables correlative mass spectrometry imaging of invading multicellular tumor spheroids
Multicellular tumor spheroids embedded in collagen I matrices are common in vitro systems for the study of solid tumors that reflect the physiological environment and complexities of the in vivo environment. While collagen I environments are physiologically relevant and permissive of cell invasion,...
Autores principales: | Avard, Rachel C., Broad, Megan L., Zandkarimi, Fereshteh, Devanny, Alexander J., Hammer, Joseph L., Yu, Karen, Guzman, Asja, Kaufman, Laura J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390472/ https://www.ncbi.nlm.nih.gov/pubmed/37524722 http://dx.doi.org/10.1038/s41598-023-38699-1 |
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