Cargando…

Schwann cells regulate tumor cells and cancer-associated fibroblasts in the pancreatic ductal adenocarcinoma microenvironment

Neuropathy is a feature more frequently observed in pancreatic ductal adenocarcinoma (PDAC) than other tumors. Schwann cells, the most prevalent cell type in peripheral nerves, migrate toward tumor cells and associate with poor prognosis in PDAC. To unveil the effects of Schwann cells on the neuro-s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xue, Meilin, Zhu, Youwei, Jiang, Yongsheng, Han, Lijie, Shi, Minmin, Su, Rui, Wang, Liwen, Xiong, Cheng, Wang, Chaofu, Wang, Ting, Deng, Shijie, Wu, Dong, Cao, Yizhi, Dong, Lei, Bai, Fan, Zhao, Shulin, Deng, Xiaxing, Peng, Chenghong, Li, Hongwei, Chen, Jianjun, Shen, Baiyong, Jiang, Lingxi, Chen, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390497/ https://www.ncbi.nlm.nih.gov/pubmed/37524695 http://dx.doi.org/10.1038/s41467-023-40314-w

Ejemplares similares

LIPH contributes to glycolytic phenotype in pancreatic ductal adenocarcinoma by activating LPA/LPAR axis and maintaining ALDOA stability
por: Han, Lijie, et al.
Publicado: (2023)

Comprehensive machine learning-generated classifier identifies pro-metastatic characteristics and predicts individual treatment in pancreatic cancer: A multicenter cohort study based on super-enhancer profiling
por: Chen, Dongjie, et al.
Publicado: (2023)

Identification of a novel immune checkpoint molecule V-set immunoglobulin domain-containing 4 that leads to impaired immunity infiltration in pancreatic ductal adenocarcinoma
por: Jiang, Yongsheng, et al.
Publicado: (2023)

Tumor-associated macrophages promote pancreatic ductal adenocarcinoma progression by inducing epithelial-to-mesenchymal transition
por: Xiong, Cheng, et al.
Publicado: (2021)

Single-cell RNA-seq analysis reveals BHLHE40-driven pro-tumour neutrophils with hyperactivated glycolysis in pancreatic tumour microenvironment
por: Wang, Liwen, et al.
Publicado: (2023)

The CTCF/LncRNA‐PACERR complex recruits E1A binding protein p300 to induce pro‐tumour macrophages in pancreatic ductal adenocarcinoma via directly regulating PTGS2 expression
por: Liu, Yihao, et al.
Publicado: (2022)

Cystatin B increases autophagic flux by sustaining proteolytic activity of cathepsin B and fuels glycolysis in pancreatic cancer: CSTB orchestrates autophagy and glycolysis in PDAC
por: Jiang, Yongsheng, et al.
Publicado: (2022)

Oncogene APOL1 promotes proliferation and inhibits apoptosis via activating NOTCH1 signaling pathway in pancreatic cancer
por: Lin, Jiewei, et al.
Publicado: (2021)

Melittin-induced long non-coding RNA NONHSAT105177 inhibits proliferation and migration of pancreatic ductal adenocarcinoma
por: Wang, Xinjing, et al.
Publicado: (2018)

The Necessity of Dissection of No. 14 Lymph Nodes to Patients With Pancreatic Ductal Adenocarcinoma Based on the Embryonic Development of the Head of the Pancreas
por: Qian, Lihan, et al.
Publicado: (2020)

Oncological outcomes of robotic-assisted versus open pancreatoduodenectomy for pancreatic ductal adenocarcinoma: a propensity score-matched analysis
por: Weng, Yuanchi, et al.
Publicado: (2020)

Real‐world implications of nonbiological factors with staging, clinical management, and prognostic prediction in pancreatic ductal adenocarcinoma
por: Wang, Chao, et al.
Publicado: (2022)

Long-term outcomes of standard versus extended lymphadenectomy in pancreatoduodenectomy for pancreatic ductal adenocarcinoma: A Chinese multi-center prospective randomized controlled trial
por: WANG, Weishen, et al.
Publicado: (2022)

The impact of Omicron pandemic and COVID‐19 vaccination on the pancreatic adenocarcinoma patients
por: Fu, Ningzhen, et al.
Publicado: (2022)

Risk factors for and prognostic values of postoperative acute kidney injury after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: A retrospective, propensity score‐matched cohort study of 1312 patients
por: Ji, Yuchen, et al.
Publicado: (2022)

Preliminary experience of the robot-assisted laparoscopic excision of a retroperitoneal mass: A case report
por: LIU, QIN, et al.
Publicado: (2014)

Higher body mass index indicated better overall survival in pancreatic ductal adenocarcinoma patients: a real-world study of 2010 patients
por: Fu, Ningzhen, et al.
Publicado: (2021)

Identification of EMT-related alternative splicing event of TMC7 to promote invasion and migration of pancreatic cancer
por: Weng, Yuanchi, et al.
Publicado: (2023)

Association between miR34b/c Polymorphism rs4938723 and Cancer Risk: A Meta-Analysis of 11 Studies including 6169 Cases and 6337 Controls
por: Wang, Xinjing, et al.
Publicado: (2014)

Systematic Review and Meta-Analysis of Pancreatic Amylase Value on Postoperative Day 1 After Pancreatic Resection to Predict Postoperative Pancreatic Fistula
por: Lu, Xiongxiong, et al.
Publicado: (2016)

Positive feedback between lncRNA FLVCR1-AS1 and KLF10 may inhibit pancreatic cancer progression via the PTEN/AKT pathway
por: Lin, Jiewei, et al.
Publicado: (2021)

H2AK119Ub1 and H3K27Me3 in molecular staging for survival prediction of patients with pancreatic ductal adenocarcinoma
por: Chen, Shi, et al.
Publicado: (2014)

Hypoxia-induced exosomal circPDK1 promotes pancreatic cancer glycolysis via c-myc activation by modulating miR-628-3p/BPTF axis and degrading BIN1
por: Lin, Jiewei, et al.
Publicado: (2022)

Development and validation of a cancer stem cell-related signature for prognostic prediction in pancreatic ductal adenocarcinoma
por: Feng, Zengyu, et al.
Publicado: (2020)

mir-329 restricts tumor growth by targeting grb2 in pancreatic cancer
por: Wang, Xinjing, et al.
Publicado: (2016)

Drug-eluting scaffold to deliver chemotherapeutic medication for management of pancreatic cancer after surgery
por: Zhan, Qian, et al.
Publicado: (2013)

Immunity-Related Gene Signature Identifies Subtypes Benefitting From Adjuvant Chemotherapy or Potentially Responding to PD1/PD-L1 Blockage in Pancreatic Cancer
por: Qian, Hao, et al.
Publicado: (2021)

Accuracy of Nodal Positivity in Inadequate Lymphadenectomy in Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma: A Population Study Using the US SEER Database
por: Wang, Weishen, et al.
Publicado: (2019)

Targeting KRAS(G12V) mutations with HLA class II-restricted TCR for the immunotherapy in solid tumors
por: Ai, Qi, et al.
Publicado: (2023)

Who could complete and benefit from the adjuvant chemotherapy regarding pancreatic ductal adenocarcinoma? A multivariate‐adjusted analysis at the pre‐adjuvant chemotherapy timing
por: Fu, Ningzhen, et al.
Publicado: (2022)

NPM1 activates metabolic changes by inhibiting FBP1 while promoting the tumorigenicity of pancreatic cancer cells
por: Zhu, Yi, et al.
Publicado: (2015)

The Immunohistochemical Evaluation of Solid Pseudopapillary Tumors of the Pancreas and Pancreatic Neuroendocrine Tumors Reveals ERO1Lβ as a New Biomarker
por: Xie, Junjie, et al.
Publicado: (2016)

Epigenetic silencing of LncRNA LINC00261 promotes c-myc-mediated aerobic glycolysis by regulating miR-222-3p/HIPK2/ERK axis and sequestering IGF2BP1
por: Zhai, Shuyu, et al.
Publicado: (2020)

A Prospective Proteomic-Based Study for Identifying Potential Biomarkers for the Diagnosis of Cholangiocarcinoma
por: Shi, Yuan, et al.
Publicado: (2013)

Preoperative plasma D-dimer independently predicts survival in patients with pancreatic ductal adenocarcinoma undergoing radical resection
por: Chen, Haoda, et al.
Publicado: (2021)

Postoperative hyperprogression disease of pancreatic ductal adenocarcinoma after curative resection: a retrospective cohort study
por: Zou, Siyi, et al.
Publicado: (2022)

Robotic-assisted versus open distal pancreatectomy for benign and low-grade malignant pancreatic tumors: a propensity score-matched study
por: Weng, Yuanchi, et al.
Publicado: (2020)

TP53 missense mutation reveals gain-of-function properties in small-sized KRAS transformed pancreatic ductal adenocarcinoma
por: Zhou, Yiran, et al.
Publicado: (2023)

Short-term Outcomes After Robot-Assisted vs Open Pancreaticoduodenectomy After the Learning Curve
por: Shi, Yusheng, et al.
Publicado: (2020)

Prognostic Analysis and Influencing Serum Biomarkers of Patients With Resectable Pancreatic Adenosquamous Cancer
por: Shi, Yusheng, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_43khqtehtgkp1beh3u7d5h38pl