Evaluation of urine dipstick tests in experimental porcine urinary tract infection with uropathogenic Escherichia coli

Urinary tract infection is a common disease in pigs and a major reason for sows to be culled. The disease, however, is difficult to diagnose due to lack of distinct clinical signs in the animals. We evaluated the diagnostic value of two commercial urine dipstick tests in 10 pigs using an experimenta...

Descripción completa

Detalles Bibliográficos
Autores principales: Stærk, Kristian, Jensen, Louise Kruse, Andersen, Thomas Emil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390499/
https://www.ncbi.nlm.nih.gov/pubmed/37524716
http://dx.doi.org/10.1038/s41598-023-39239-7
_version_ 1785082488198004736
author Stærk, Kristian
Jensen, Louise Kruse
Andersen, Thomas Emil
author_facet Stærk, Kristian
Jensen, Louise Kruse
Andersen, Thomas Emil
author_sort Stærk, Kristian
collection PubMed
description Urinary tract infection is a common disease in pigs and a major reason for sows to be culled. The disease, however, is difficult to diagnose due to lack of distinct clinical signs in the animals. We evaluated the diagnostic value of two commercial urine dipstick tests in 10 pigs using an experimental model of Escherichia coli urinary tract infection. Urine collected at baseline and 48 h after inoculation were analyzed. We show that dipstick tests positive of blood, leucocytes and particularly nitrite are very specific for E. coli UTI with a 100% positive predictive value.
format Online
Article
Text
id pubmed-10390499
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-103904992023-08-02 Evaluation of urine dipstick tests in experimental porcine urinary tract infection with uropathogenic Escherichia coli Stærk, Kristian Jensen, Louise Kruse Andersen, Thomas Emil Sci Rep Article Urinary tract infection is a common disease in pigs and a major reason for sows to be culled. The disease, however, is difficult to diagnose due to lack of distinct clinical signs in the animals. We evaluated the diagnostic value of two commercial urine dipstick tests in 10 pigs using an experimental model of Escherichia coli urinary tract infection. Urine collected at baseline and 48 h after inoculation were analyzed. We show that dipstick tests positive of blood, leucocytes and particularly nitrite are very specific for E. coli UTI with a 100% positive predictive value. Nature Publishing Group UK 2023-07-31 /pmc/articles/PMC10390499/ /pubmed/37524716 http://dx.doi.org/10.1038/s41598-023-39239-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Stærk, Kristian
Jensen, Louise Kruse
Andersen, Thomas Emil
Evaluation of urine dipstick tests in experimental porcine urinary tract infection with uropathogenic Escherichia coli
title Evaluation of urine dipstick tests in experimental porcine urinary tract infection with uropathogenic Escherichia coli
title_full Evaluation of urine dipstick tests in experimental porcine urinary tract infection with uropathogenic Escherichia coli
title_fullStr Evaluation of urine dipstick tests in experimental porcine urinary tract infection with uropathogenic Escherichia coli
title_full_unstemmed Evaluation of urine dipstick tests in experimental porcine urinary tract infection with uropathogenic Escherichia coli
title_short Evaluation of urine dipstick tests in experimental porcine urinary tract infection with uropathogenic Escherichia coli
title_sort evaluation of urine dipstick tests in experimental porcine urinary tract infection with uropathogenic escherichia coli
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390499/
https://www.ncbi.nlm.nih.gov/pubmed/37524716
http://dx.doi.org/10.1038/s41598-023-39239-7
work_keys_str_mv AT stærkkristian evaluationofurinedipsticktestsinexperimentalporcineurinarytractinfectionwithuropathogenicescherichiacoli
AT jensenlouisekruse evaluationofurinedipsticktestsinexperimentalporcineurinarytractinfectionwithuropathogenicescherichiacoli
AT andersenthomasemil evaluationofurinedipsticktestsinexperimentalporcineurinarytractinfectionwithuropathogenicescherichiacoli

Ejemplares similares