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Utility of genetic risk scores in type 1 diabetes

Iterative advances in understanding of the genetics of type 1 diabetes have identified >70 genetic regions associated with risk of the disease, including strong associations across the HLA class II region that account for >50% of heritability. The increased availability of genetic data combine...

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Detalles Bibliográficos
Autores principales: Luckett, Amber M., Weedon, Michael N., Hawkes, Gareth, Leslie, R. David, Oram, Richard A., Grant, Struan F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390619/
https://www.ncbi.nlm.nih.gov/pubmed/37439792
http://dx.doi.org/10.1007/s00125-023-05955-y