Cargando…

Untangling Alzheimer’s disease with spatial multi-omics: a brief review

Alzheimer’s disease (AD) is the most common form of neurological dementia, specified by extracellular β-amyloid plaque deposition, neurofibrillary tangles, and cognitive impairment. AD-associated pathologies like cerebral amyloid angiopathy (CAA) are also affiliated with cognitive impairment and hav...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marshall, Cody R., Farrow, Melissa A., Djambazova, Katerina V., Spraggins, Jeffrey M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390637/ https://www.ncbi.nlm.nih.gov/pubmed/37533766 http://dx.doi.org/10.3389/fnagi.2023.1150512

Ejemplares similares

Automated biomarker candidate discovery in imaging mass spectrometry data through spatially localized Shapley additive explanations
por: Tideman, Leonoor E.M., et al.
Publicado: (2021)

Untangling Alzheimer's Therapy
Publicado: (2004)

Untangling the Tauopathy for Alzheimer’s disease and parkinsonism
por: Chang, Hui-Yun, et al.
Publicado: (2018)

Untangling the Manganese-α-Synuclein Web
por: Peres, Tanara Vieira, et al.
Publicado: (2016)

Untangling the Conformational Polymorphism of Disordered Proteins Associated With Neurodegeneration at the Single-Molecule Level
por: Birol, Melissa, et al.
Publicado: (2020)

Editorial: Untangling the Role of Tau in Physiology and Pathology
por: Medina, Miguel, et al.
Publicado: (2020)

The promise of multi-omics approaches to discover biological alterations with clinical relevance in Alzheimer’s disease
por: Clark, Christopher, et al.
Publicado: (2022)

Untangling Neural Networks with Dual Retrograde Transsynaptic Viral Infection
por: Ohara, Shinya, et al.
Publicado: (2009)

Untangling Tau and Iron: Exploring the Interaction Between Iron and Tau in Neurodegeneration
por: Rao, Shalini S., et al.
Publicado: (2018)

Representational untangling by the firing rate nonlinearity in V1 simple cells
por: Gáspár, Merse E, et al.
Publicado: (2019)

Untangling Cortico-Striatal Connectivity and Cross-Frequency Coupling in L-DOPA-Induced Dyskinesia
por: Belić, Jovana J., et al.
Publicado: (2016)

Toward a computational theory of manifold untangling: from global embedding to local flattening
por: Li, Xin, et al.
Publicado: (2023)

Imaging mass spectrometry reveals complex lipid distributions across Staphylococcus aureus biofilm layers
por: Rivera, Emilio S., et al.
Publicado: (2022)

Untangling the Etiology of Ascites
por: Lopez-Molina, Michael, et al.
Publicado: (2015)

Uncovering neuroinflammation-related modules and potential repurposing drugs for Alzheimer's disease through multi-omics data integrative analysis
por: Li, Shensuo, et al.
Publicado: (2023)

Using light and X-ray scattering to untangle complex neuronal orientations and validate diffusion MRI
por: Menzel, Miriam, et al.
Publicado: (2023)

SM-Omics is an automated platform for high-throughput spatial multi-omics
por: Vickovic, S., et al.
Publicado: (2022)

Exercise Modifies the Transcriptional Regulatory Features of Monocytes in Alzheimer’s Patients: A Multi-Omics Integration Analysis Based on Single Cell Technology
por: Chen, Yisheng, et al.
Publicado: (2022)

Untangling the association of amyloid-β and tau with synaptic and axonal loss in Alzheimer’s disease
por: Pereira, Joana B, et al.
Publicado: (2020)

Editorial: Multi-modality imaging and multi-omics approach to pediatric neurogenetic disorders
por: Dong, Xinran
Publicado: (2023)

Uncovering Molecular Heterogeneity in the Kidney With Spatially Targeted Mass Spectrometry
por: Kruse, Angela R. S., et al.
Publicado: (2022)

Multi-omic atlas of the parahippocampal gyrus in Alzheimer’s disease
por: Coleman, Claire, et al.
Publicado: (2023)

Homicide, Inequality, and Climate: Untangling the Relationships
por: Kuznar, Lawrence A., et al.
Publicado: (2021)

Dissecting the brain with spatially resolved multi-omics
por: Fangma, Yijia, et al.
Publicado: (2023)

Shuffle & untangle: novel untangle methods for solving the tanglegram layout problem
por: Nguyen, Nghia, et al.
Publicado: (2022)

Editorial: Multi-omics, Epigenomics, and Computational Analysis of Neurodegenerative Disorders
por: Jaiswal, Manoj Kumar
Publicado: (2022)

Untangle network security
por: El-Bawab, Abd El-Monem A
Publicado: (2014)

Untangling tau imaging
por: Villemagne, Victor L., et al.
Publicado: (2016)

Untangling the threads of cellulose mercerization
por: Sawada, Daisuke, et al.
Publicado: (2022)

An integrated neuroimaging-omics approach for the gut-brain communication pathways in Alzheimer’s disease
por: Sheng, Can, et al.
Publicado: (2023)

From Multi-Omics Approaches to Precision Medicine in Amyotrophic Lateral Sclerosis
por: Morello, Giovanna, et al.
Publicado: (2020)

Spatial multi-omic map of human myocardial infarction
por: Kuppe, Christoph, et al.
Publicado: (2022)

Spatial multi-omics analyses of the tumor immune microenvironment
por: Hsieh, Wan-Chen, et al.
Publicado: (2022)

Methods and applications for single-cell and spatial multi-omics
por: Vandereyken, Katy, et al.
Publicado: (2023)

Untangling the Heterogeneity of Acquired Generalized Lipodystrophy
por: Cavdar, Umit, et al.
Publicado: (2021)

Untangling the Web of Systemic Autoinflammatory Diseases
por: Rigante, Donato, et al.
Publicado: (2014)

Untangling the immune basis of disease susceptibility
por: Ribeiro, Ruy M, et al.
Publicado: (2020)

Advances in Astrocyte Computational Models: From Metabolic Reconstructions to Multi-omic Approaches
por: González, Janneth, et al.
Publicado: (2020)

Multi-omic profiling of the developing human cerebral cortex at the single-cell level
por: Zhu, Kaiyi, et al.
Publicado: (2023)

Cell-based therapy in Alzheimer's disease: can human fetal cholinergic neurons “untangle the skein”?
por: Guarnieri, Giulia, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_tjjdocoinb6o4ldq0jnop69ofu