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Negative regulation of pro-apoptotic AMPK/JNK pathway by itaconate in mice with fulminant liver injury
Accumulating evidence indicates that metabolic responses are deeply integrated into signal transduction, which provides novel opportunities for the metabolic control of various disorders. Recent studies suggest that itaconate, a highly concerned bioactive metabolite catalyzed by immune responsive ge...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390640/ https://www.ncbi.nlm.nih.gov/pubmed/37524706 http://dx.doi.org/10.1038/s41419-023-06001-w |