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The value of multimodal ultrasonography in evaluating therapeutic response of cervical tuberculous lymphadenitis to anti-tuberculosis drugs

PURPOSE: In order to research the value of multimodal ultrasonography in evaluating therapeutic response of cervical tuberculous lymphadenitis to anti-tuberculosis drugs. MATERIALS AND METHODS: Sixty-one patients with cervical tuberculous lymphadenitis were enrolled in this study. Ultrasound examina...

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Autores principales: Yu, Tianzhuo, Zhang, Lin, Xu, Jianping, Meng, Jun, Yu, Xiulei, Zhang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390732/
https://www.ncbi.nlm.nih.gov/pubmed/37534316
http://dx.doi.org/10.3389/fmed.2023.1177045
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author Yu, Tianzhuo
Zhang, Lin
Xu, Jianping
Meng, Jun
Yu, Xiulei
Zhang, Ying
author_facet Yu, Tianzhuo
Zhang, Lin
Xu, Jianping
Meng, Jun
Yu, Xiulei
Zhang, Ying
author_sort Yu, Tianzhuo
collection PubMed
description PURPOSE: In order to research the value of multimodal ultrasonography in evaluating therapeutic response of cervical tuberculous lymphadenitis to anti-tuberculosis drugs. MATERIALS AND METHODS: Sixty-one patients with cervical tuberculous lymphadenitis were enrolled in this study. Ultrasound examination was performed before systemic standard anti-tuberculosis treatment and within 1–2 months after treatment, and the patients were divided into effective group and ineffective group according to the follow-up at the sixth month. The multimodal ultrasound signs of the two groups were compared and analyzed. RESULTS: In the effective group, there were significant differences in the maximum diameter of lymph nodes, the echo of the surrounding tissue and the enlargement of the contrast area before and after treatment (p < 0.05). At 1–2 months after treatment, there were significant differences in the maximum diameter, pus changes, CDFI, elasticity scores, echo of surrounding tissues, changes in enlarged and non-enhanced areas after contrast enhancement between the effective group and the ineffective group (p < 0.05). CONCLUSION: The multimodal ultrasound signs of the appearance of internal pus or non-enhancement area enlargement, enhanced echo of the surrounding tissue and enlargement after CEUS are related to poor prognosis, and may be used to evaluate the response of anti-tuberculosis chemotherapy when the size change of lymph node is not obvious in individual treatment.
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spelling pubmed-103907322023-08-02 The value of multimodal ultrasonography in evaluating therapeutic response of cervical tuberculous lymphadenitis to anti-tuberculosis drugs Yu, Tianzhuo Zhang, Lin Xu, Jianping Meng, Jun Yu, Xiulei Zhang, Ying Front Med (Lausanne) Medicine PURPOSE: In order to research the value of multimodal ultrasonography in evaluating therapeutic response of cervical tuberculous lymphadenitis to anti-tuberculosis drugs. MATERIALS AND METHODS: Sixty-one patients with cervical tuberculous lymphadenitis were enrolled in this study. Ultrasound examination was performed before systemic standard anti-tuberculosis treatment and within 1–2 months after treatment, and the patients were divided into effective group and ineffective group according to the follow-up at the sixth month. The multimodal ultrasound signs of the two groups were compared and analyzed. RESULTS: In the effective group, there were significant differences in the maximum diameter of lymph nodes, the echo of the surrounding tissue and the enlargement of the contrast area before and after treatment (p < 0.05). At 1–2 months after treatment, there were significant differences in the maximum diameter, pus changes, CDFI, elasticity scores, echo of surrounding tissues, changes in enlarged and non-enhanced areas after contrast enhancement between the effective group and the ineffective group (p < 0.05). CONCLUSION: The multimodal ultrasound signs of the appearance of internal pus or non-enhancement area enlargement, enhanced echo of the surrounding tissue and enlargement after CEUS are related to poor prognosis, and may be used to evaluate the response of anti-tuberculosis chemotherapy when the size change of lymph node is not obvious in individual treatment. Frontiers Media S.A. 2023-07-18 /pmc/articles/PMC10390732/ /pubmed/37534316 http://dx.doi.org/10.3389/fmed.2023.1177045 Text en Copyright © 2023 Yu, Zhang, Xu, Meng, Yu and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Yu, Tianzhuo
Zhang, Lin
Xu, Jianping
Meng, Jun
Yu, Xiulei
Zhang, Ying
The value of multimodal ultrasonography in evaluating therapeutic response of cervical tuberculous lymphadenitis to anti-tuberculosis drugs
title The value of multimodal ultrasonography in evaluating therapeutic response of cervical tuberculous lymphadenitis to anti-tuberculosis drugs
title_full The value of multimodal ultrasonography in evaluating therapeutic response of cervical tuberculous lymphadenitis to anti-tuberculosis drugs
title_fullStr The value of multimodal ultrasonography in evaluating therapeutic response of cervical tuberculous lymphadenitis to anti-tuberculosis drugs
title_full_unstemmed The value of multimodal ultrasonography in evaluating therapeutic response of cervical tuberculous lymphadenitis to anti-tuberculosis drugs
title_short The value of multimodal ultrasonography in evaluating therapeutic response of cervical tuberculous lymphadenitis to anti-tuberculosis drugs
title_sort value of multimodal ultrasonography in evaluating therapeutic response of cervical tuberculous lymphadenitis to anti-tuberculosis drugs
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390732/
https://www.ncbi.nlm.nih.gov/pubmed/37534316
http://dx.doi.org/10.3389/fmed.2023.1177045
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