A novel organotypic cortical slice culture model for traumatic brain injury: molecular changes induced by injury and mesenchymal stromal cell secretome treatment

Traumatic brain injury (TBI) is a major worldwide neurological disorder with no neuroprotective treatment available. Three-dimensional (3D) in vitro models of brain contusion serving as a screening platform for drug testing are lacking. Here we developed a new in vitro model of brain contusion on or...

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Detalles Bibliográficos
Autores principales: Pischiutta, Francesca, Cavaleiro, Helena, Caruso, Enrico, Tribuzio, Francesca, Di Marzo, Noemi, Moro, Federico, Kobeissy, Firas, Wang, Kevin K., Salgado, António J., Zanier, Elisa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390737/
https://www.ncbi.nlm.nih.gov/pubmed/37534042
http://dx.doi.org/10.3389/fncel.2023.1217987

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