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Photoredox catalysis harvesting multiple photon or electrochemical energies
Photoredox catalysis (PRC) is a cutting-edge frontier for single electron-transfer (SET) reactions, enabling the generation of reactive intermediates for both oxidative and reductive processes via photon activation of a catalyst. Although this represents a significant step towards chemoselective and...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Beilstein-Institut
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390843/ https://www.ncbi.nlm.nih.gov/pubmed/37533877 http://dx.doi.org/10.3762/bjoc.19.81 |
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author | Lepori, Mattia Schmid, Simon Barham, Joshua P |
author_facet | Lepori, Mattia Schmid, Simon Barham, Joshua P |
author_sort | Lepori, Mattia |
collection | PubMed |
description | Photoredox catalysis (PRC) is a cutting-edge frontier for single electron-transfer (SET) reactions, enabling the generation of reactive intermediates for both oxidative and reductive processes via photon activation of a catalyst. Although this represents a significant step towards chemoselective and, more generally, sustainable chemistry, its efficacy is limited by the energy of visible light photons. Nowadays, excellent alternative conditions are available to overcome these limitations, harvesting two different but correlated concepts: the use of multi-photon processes such as consecutive photoinduced electron transfer (conPET) and the combination of photo- and electrochemistry in synthetic photoelectrochemistry (PEC). Herein, we review the most recent contributions to these fields in both oxidative and reductive activations of organic functional groups. New opportunities for organic chemists are captured, such as selective reactions employing super-oxidants and super-reductants to engage unactivated chemical feedstocks, and scalability up to gram scales in continuous flow. This review provides comparisons between the two techniques (multi-photon photoredox catalysis and PEC) to help the reader to fully understand their similarities, differences and potential applications and to therefore choose which method is the most appropriate for a given reaction, scale and purpose of a project. |
format | Online Article Text |
id | pubmed-10390843 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Beilstein-Institut |
record_format | MEDLINE/PubMed |
spelling | pubmed-103908432023-08-02 Photoredox catalysis harvesting multiple photon or electrochemical energies Lepori, Mattia Schmid, Simon Barham, Joshua P Beilstein J Org Chem Review Photoredox catalysis (PRC) is a cutting-edge frontier for single electron-transfer (SET) reactions, enabling the generation of reactive intermediates for both oxidative and reductive processes via photon activation of a catalyst. Although this represents a significant step towards chemoselective and, more generally, sustainable chemistry, its efficacy is limited by the energy of visible light photons. Nowadays, excellent alternative conditions are available to overcome these limitations, harvesting two different but correlated concepts: the use of multi-photon processes such as consecutive photoinduced electron transfer (conPET) and the combination of photo- and electrochemistry in synthetic photoelectrochemistry (PEC). Herein, we review the most recent contributions to these fields in both oxidative and reductive activations of organic functional groups. New opportunities for organic chemists are captured, such as selective reactions employing super-oxidants and super-reductants to engage unactivated chemical feedstocks, and scalability up to gram scales in continuous flow. This review provides comparisons between the two techniques (multi-photon photoredox catalysis and PEC) to help the reader to fully understand their similarities, differences and potential applications and to therefore choose which method is the most appropriate for a given reaction, scale and purpose of a project. Beilstein-Institut 2023-07-28 /pmc/articles/PMC10390843/ /pubmed/37533877 http://dx.doi.org/10.3762/bjoc.19.81 Text en Copyright © 2023, Lepori et al. https://creativecommons.org/licenses/by/4.0/This is an open access article licensed under the terms of the Beilstein-Institut Open Access License Agreement (https://www.beilstein-journals.org/bjoc/terms/terms), which is identical to the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ). The reuse of material under this license requires that the author(s), source and license are credited. Third-party material in this article could be subject to other licenses (typically indicated in the credit line), and in this case, users are required to obtain permission from the license holder to reuse the material. |
spellingShingle | Review Lepori, Mattia Schmid, Simon Barham, Joshua P Photoredox catalysis harvesting multiple photon or electrochemical energies |
title | Photoredox catalysis harvesting multiple photon or electrochemical energies |
title_full | Photoredox catalysis harvesting multiple photon or electrochemical energies |
title_fullStr | Photoredox catalysis harvesting multiple photon or electrochemical energies |
title_full_unstemmed | Photoredox catalysis harvesting multiple photon or electrochemical energies |
title_short | Photoredox catalysis harvesting multiple photon or electrochemical energies |
title_sort | photoredox catalysis harvesting multiple photon or electrochemical energies |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390843/ https://www.ncbi.nlm.nih.gov/pubmed/37533877 http://dx.doi.org/10.3762/bjoc.19.81 |
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