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Genomic Profiling of Radiation-Induced Sarcomas Reveals the Immunologic Characteristics and Its Response to Immune Checkpoint Blockade

PURPOSE: Radiation-induced sarcomas (RIS) have a poor prognosis and lack effective treatments. Its genome and tumor microenvironment are not well characterized and need further exploration. EXPERIMENTAL DESIGN: Here, we performed whole-exome sequencing (WES) and mRNA sequencing (mRNA-seq) on patient...

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Detalles Bibliográficos
Autores principales:	Hong, Dong-Chun, Yang, Jing, Sun, Cong, Liu, Yuan-Tao, Shen, Lu-Jun, Xu, Bu-Shu, Que, Yi, Xia, Xiaojun, Zhang, Xing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Translational Cancer Mechanisms and Therapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390862/ https://www.ncbi.nlm.nih.gov/pubmed/37184976 http://dx.doi.org/10.1158/1078-0432.CCR-22-3567

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