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Concomitant Filled Prescriptions of Oxymorphone or Oxycodone with CYP3A Inhibitors and Inducers

BACKGROUND: Oxymorphone’s metabolism does not involve the hepatic cytochrome P450 (CYP) system. The effect of this pharmacokinetic feature of oxymorphone on opioid prescribing is unknown. OBJECTIVE: To assess the relative frequency with which oxymorphone and oxycodone (a CYP3A-metabolized opioid ana...

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Detalles Bibliográficos
Autores principales:	Coyle, D. Tyler, Woodworth, Tiffany S., Moeny, David, Staffa, Judy, Meyer, Tamra, Woods, Corinne, Welch, Emily C., Haynes, Kevin, Toh, Sengwee, Maro, Judith C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academy of Managed Care Pharmacy 2020
Materias:	Research Brief
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391052/ https://www.ncbi.nlm.nih.gov/pubmed/32347183 http://dx.doi.org/10.18553/jmcp.2020.26.5.668

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