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Prevalence and Landscape of Pathogenic or Likely Pathogenic Germline Variants and Their Association With Somatic Phenotype in Unselected Chinese Patients With Gynecologic Cancers

IMPORTANCE: Understanding germline and somatic status in patients with gynecologic cancers could improve risk assessment and guide therapeutic decision-making. OBJECTIVE: To evaluate the prevalence and landscape of germline pathogenic or likely pathogenic (P/LP) variants and explore whether these va...

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Detalles Bibliográficos
Autores principales: Wen, Hao, Xu, Qin, Sheng, Xiujie, Li, Huawen, Wang, Xipeng, Wu, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391307/
https://www.ncbi.nlm.nih.gov/pubmed/37523182
http://dx.doi.org/10.1001/jamanetworkopen.2023.26437

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