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Causal effects of circulating cytokine concentrations on risk of Alzheimer’s disease and cognitive function

BACKGROUND: There is considerable evidence suggesting a role of neuroinflammation in the pathogenesis of Alzheimer’s disease. Establishing causality is challenging due to bias from reverse causation and residual confounding. METHODS: We used two-sample MR to explore causal effects of circulating cyt...

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Detalles Bibliográficos
Autores principales:	Pagoni, Panagiota, Korologou-Linden, Roxanna S., Howe, Laura D., Davey Smith, George, Ben-Shlomo, Yoav, Stergiakouli, Evie, Anderson, Emma L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Full-length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391322/ https://www.ncbi.nlm.nih.gov/pubmed/35580794 http://dx.doi.org/10.1016/j.bbi.2022.05.006

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