Prevalence and Clinical Implications of a β-Amyloid–Negative, Tau-Positive Cerebrospinal Fluid Biomarker Profile in Alzheimer Disease

IMPORTANCE: Knowledge is lacking on the prevalence and prognosis of individuals with a β-amyloid–negative, tau-positive (A−T+) cerebrospinal fluid (CSF) biomarker profile. OBJECTIVE: To estimate the prevalence of a CSF A−T+ biomarker profile and investigate its clinical implications. DESIGN, SETTING...

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Detalles Bibliográficos
Autores principales: Erickson, Pontus, Simrén, Joel, Brum, Wagner S., Ennis, Gilda E., Kollmorgen, Gwendlyn, Suridjan, Ivonne, Langhough, Rebecca, Jonaitis, Erin M., Van Hulle, Carol A., Betthauser, Tobey J., Carlsson, Cynthia M., Asthana, Sanjay, Ashton, Nicholas J., Johnson, Sterling C., Shaw, Leslie M., Blennow, Kaj, Andreasson, Ulf, Bendlin, Barbara B., Zetterberg, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391361/
https://www.ncbi.nlm.nih.gov/pubmed/37523162
http://dx.doi.org/10.1001/jamaneurol.2023.2338

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