Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1

Galectins are a group of carbohydrate-binding proteins with a presumed immunomodulatory role and an elusive function on antigen-presenting cells. Here we analyzed the expression of galectin-1 and found upregulation of galectin-1 in the extracellular matrix across multiple tumors. Performing an in-de...

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Detalles Bibliográficos
Autores principales: Rudjord-Levann, Asha M., Ye, Zilu, Hafkenscheid, Lise, Horn, Sabrina, Wiegertjes, Renske, Nielsen, Mathias A.I., Song, Ming, Mathiesen, Caroline B.K., Stoop, Jesse, Stowell, Sean, Straten, Per Thor, Leffler, Hakon, Vakhrushev, Sergey Y., Dabelsteen, Sally, Olsen, Jesper V., Wandall, Hans H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391608/
https://www.ncbi.nlm.nih.gov/pubmed/37534161
http://dx.doi.org/10.1016/j.isci.2023.106984

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