Cargando…

Momordicine I suppresses glioma growth by promoting apoptosis and impairing mitochondrial oxidative phosphorylation

Glioblastoma (GBM) is the most common type of primary brain tumor. Patients with GBM have poor survival outcomes. Isolated components of Momordica charantia have anticancer effects. However, the bioactivity of M. charantia extracts against GBM remains unknown. We tested four major extracts of M. cha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kao, Ying, Chou, Chung-Hsing, Huang, Li-Chun, Tsai, Chia-Kuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Leibniz Research Centre for Working Environment and Human Factors 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391611/ https://www.ncbi.nlm.nih.gov/pubmed/37534227 http://dx.doi.org/10.17179/excli2023-6129

Ejemplares similares

Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ
por: Li, Hongming, et al.
Publicado: (2023)

Inhibitory Effects of Momordicine I on High-Glucose-Induced Cell Proliferation and Collagen Synthesis in Rat Cardiac Fibroblasts
por: Chen, Po-Yuan, et al.
Publicado: (2018)

Corrigendum to “Inhibitory Effects of Momordicine I on High-Glucose-Induced Cell Proliferation and Collagen Synthesis in Rat Cardiac Fibroblasts”
por: Chen, Po-Yuan, et al.
Publicado: (2019)

Antiproliferative and apoptotic effects of telmisartan in human glioma cells
por: Chang, Yung-Lung, et al.
Publicado: (2023)

Momordicine-I, a Bitter Melon Bioactive Metabolite, Displays Anti-Tumor Activity in Head and Neck Cancer Involving c-Met and Downstream Signaling
por: Sur, Subhayan, et al.
Publicado: (2021)

ARID4B Knockdown Suppresses PI3K/AKT Signaling and Induces Apoptosis in Human Glioma Cells
por: Luo, Siou-Min, et al.
Publicado: (2021)

ETMM-06. ELEVATED MITOCHONDRIAL TOM20 EXPRESSION SUPPRESSES GLIOMA MALIGNANCY BY ENHANCING OXIDATIVE PHOSPHORYLATION
por: Li, Mao, et al.
Publicado: (2021)

Global-cognitive health metrics: A novel approach for assessing cognition impairment in adult population
por: Tsai, Chia-Kuang, et al.
Publicado: (2018)

Mitochondrial Oxidative Phosphorylation Is Impaired in Patients with Congenital Lipodystrophy
por: Sleigh, Alison, et al.
Publicado: (2012)

Suppression of Mic60 compromises mitochondrial transcription and oxidative phosphorylation
por: Yang, Rui-Feng, et al.
Publicado: (2015)

Diosmin Inhibits Glioblastoma Growth through Inhibition of Autophagic Flux
por: Chang, Yung-Lung, et al.
Publicado: (2021)

Mitochondrial Lon-induced mitophagy benefits hypoxic resistance via Ca(2+)-dependent FUNDC1 phosphorylation at the ER-mitochondria interface
por: Ponneri Babuharisankar, Ananth, et al.
Publicado: (2023)

Bcl-2 Suppresses Oxidative Phosphorylation Defects Caused by Mitochondrial DNA Mutations
por: Manfredi, Giovanni, et al.
Publicado: (2001)

Polyphyllin I suppresses proliferation and promotes apoptosis of gastric cancer cell by inhibiting stat3 phosphorylation
por: Han, Jun, et al.
Publicado: (2020)

The mechanisms of action of mitochondrial targeting agents in cancer: inhibiting oxidative phosphorylation and inducing apoptosis
por: Yang, Yi, et al.
Publicado: (2023)

Chrysophanol Induced Glioma Cells Apoptosis via Activation of Mitochondrial Apoptosis Pathway
por: Gu, Jia, et al.
Publicado: (2021)

Mitochondrial Lon sequesters and stabilizes p53 in the matrix to restrain apoptosis under oxidative stress via its chaperone activity
por: Sung, Ya-Ju, et al.
Publicado: (2018)

GSK3beta-Mediated Drp1 Phosphorylation Induced Elongated Mitochondrial Morphology against Oxidative Stress
por: Chou, Chia-Hua, et al.
Publicado: (2012)

Antiproliferative Effects of the Natural Oxadiazine Nocuolin A Are Associated With Impairment of Mitochondrial Oxidative Phosphorylation
por: Sousa, Maria Lígia, et al.
Publicado: (2019)

Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen
por: Vardhana, Santosha A., et al.
Publicado: (2020)

Sesamol Induces Human Hepatocellular Carcinoma Cells Apoptosis by Impairing Mitochondrial Function and Suppressing Autophagy
por: Liu, Zhigang, et al.
Publicado: (2017)

Pterostilbene promotes mitochondrial apoptosis and inhibits proliferation in glioma cells
por: Gao, Haijun, et al.
Publicado: (2021)

Inhibition of STAT3(Y705) phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells
por: Guo, Hangcheng, et al.
Publicado: (2022)

Noncanonical mitochondrial unfolded protein response impairs placental oxidative phosphorylation in early-onset preeclampsia
por: Yung, Hong Wa, et al.
Publicado: (2019)

Copper depletion modulates mitochondrial oxidative phosphorylation to impair triple negative breast cancer metastasis
por: Ramchandani, Divya, et al.
Publicado: (2021)

Corrigendum: Antiproliferative effects of the natural oxadiazine Nocuolin A are associated with impairment of mitochondrial oxidative phosphorylation
por: Sousa, Maria Lígia, et al.
Publicado: (2023)

Control mechanisms in mitochondrial oxidative phosphorylation
por: Hroudová, Jana, et al.
Publicado: (2013)

Mitochondrial oxidative phosphorylation in cutaneous melanoma
por: Kumar, Prakrit R., et al.
Publicado: (2020)

Endoplasmic Reticulum Stress Contributed to Dipyridamole-Induced Impaired Autophagic Flux and Glioma Apoptosis
por: Chang, Cheng-Yi, et al.
Publicado: (2022)

Oxidative Phosphorylation Impairment by DDT and DDE
por: Elmore, Sarah E., et al.
Publicado: (2019)

CKAP2L Knockdown Exerts Antitumor Effects by Increasing miR-4496 in Glioblastoma Cell Lines
por: Li, Yao-Feng, et al.
Publicado: (2020)

Cyclin G2 Inhibits the Warburg Effect and Tumour Progression by Suppressing LDHA Phosphorylation in Glioma
por: Li, Sen, et al.
Publicado: (2019)

Accumulation of cholesterol suppresses oxidative phosphorylation and altered responses to inflammatory stimuli of macrophages
por: Chiu, Yi-Chou, et al.
Publicado: (2021)

Overexpression of PLOD3 promotes tumor progression and poor prognosis in gliomas
por: Tsai, Chia-Kuang, et al.
Publicado: (2018)

Extracellular Regulated Kinase Phosphorylates Mitofusin 1 to Control Mitochondrial Morphology and Apoptosis
por: Pyakurel, Aswin, et al.
Publicado: (2015)

Cloperastine inhibits esophageal squamous cell carcinoma proliferation in vivo and in vitro by suppressing mitochondrial oxidative phosphorylation
por: Li, Bo, et al.
Publicado: (2021)

Impaired Cerebral Mitochondrial Oxidative Phosphorylation Function in a Rat Model of Ventricular Fibrillation and Cardiopulmonary Resuscitation
por: Jiang, Jun, et al.
Publicado: (2014)

Impaired Mitochondrial Fusion and Oxidative Phosphorylation Triggered by High Glucose Is Mediated by Tom22 in Endothelial Cells
por: Zeng, Yi, et al.
Publicado: (2019)

Mitochondrial Complex I Inhibitors and Forced Oxidative Phosphorylation Synergize in Inducing Cancer Cell Death
por: Palorini, Roberta, et al.
Publicado: (2013)

JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis
por: Huntwork-Rodriguez, Sarah, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_0s0ht51po01pgl029b68i94a95