Peroxisome proliferator activated receptor-γ in osteoblasts controls bone formation and fat mass by regulating sclerostin expression

The nuclear receptor peroxisome proliferator activated receptor-γ (PPARγ) is a key contributor to metabolic function via its adipogenic and insulin-sensitizing functions, but it has negative effects on skeletal homeostasis. Here, we questioned whether the skeletal and metabolic actions of PPARγ are...

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Detalles Bibliográficos
Autores principales: Kim, Soohyun P., Seward, Avery H., Garcia-Diaz, Jean, Alekos, Nathalie, Gould, Nicole R., Aja, Susan, Stains, Joseph P., Wolfgang, Michael J., Riddle, Ryan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391670/
https://www.ncbi.nlm.nih.gov/pubmed/37534168
http://dx.doi.org/10.1016/j.isci.2023.106999

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