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Tissue specificity of oncogenic BRAF targeted to lung and thyroid through a shared lineage factor

Cells of origin in cancer determine tumor phenotypes, but whether lineage-defining transcription factors might influence tissue specificity of tumorigenesis among organs with similar developmental traits are unknown. We demonstrate here that tumor development and progression markedly differ in lung...

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Detalles Bibliográficos
Autores principales: Schoultz, Elin, Liang, Shawn, Carlsson, Therese, Filges, Stefan, Ståhlberg, Anders, Fagman, Henrik, Wiel, Clotilde, Sayin, Volkan, Nilsson, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391731/
https://www.ncbi.nlm.nih.gov/pubmed/37534159
http://dx.doi.org/10.1016/j.isci.2023.107071