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Valproic acid increases CAR T cell cytotoxicity against acute myeloid leukemia

The treatment of B cell malignancies has dramatically changed with the introduction of immunotherapy, especially chimeric antigen receptor T (CAR-T) cell therapy. However, only limited efficacy is observed in acute myeloid leukaemia (AML). In the study, We detected CD123 and CLL-1 expression on leuk...

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Detalles Bibliográficos
Autores principales:	Wen, Jingjing, Chen, Yanxin, Yang, Jiajie, Dai, Chunye, Yu, Shenjie, Zhong, Wenting, Liu, Lilin, He, Chengguanng, Zhang, Wenmin, Yang, Ting, Liu, Lingfeng, Hu, Jianda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391797/ https://www.ncbi.nlm.nih.gov/pubmed/37524506 http://dx.doi.org/10.1136/jitc-2023-006857

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