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Role and significance of SIRT1 in regulating the LPS-activated pyroptosis pathway in children with congenital hydronephrosis

OBJECTIVE: To explore the characteristics and mechanism of sirtuin 1 (SIRT1) in lipopolysaccharide (LPS)-activated pyroptosis in the renal tissue of children with congenital hydronephrosis (CHn). METHODS: We detected the expression characteristics and clinical significance of SIRT1 and pyroptosis pa...

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Detalles Bibliográficos
Autores principales: Wang, Zhan, Weizhong, Gu, Zhou, Juan, Tang, Daxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391807/
https://www.ncbi.nlm.nih.gov/pubmed/37534327
http://dx.doi.org/10.1136/wjps-2023-000602