Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis

BACKGROUND: Irritable bowel syndrome (IBS) often co-occurs with psychiatric and gastrointestinal disorders. A recent genome-wide association study (GWAS) identified several genetic risk variants for IBS. However, most of the heritability remains unidentified, and the genetic overlap with psychiatric...

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Detalles Bibliográficos
Autores principales: Tesfaye, Markos, Jaholkowski, Piotr, Hindley, Guy F. L., Shadrin, Alexey A., Rahman, Zillur, Bahrami, Shahram, Lin, Aihua, Holen, Børge, Parker, Nadine, Cheng, Weiqiu, Rødevand, Linn, Frei, Oleksandr, Djurovic, Srdjan, Dale, Anders M., Smeland, Olav B., O’Connell, Kevin S., Andreassen, Ole A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391890/
https://www.ncbi.nlm.nih.gov/pubmed/37528461
http://dx.doi.org/10.1186/s13073-023-01212-4

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