Cargando…

Spatio-chromatic vision with multifocal diffractive intraocular lens

BACKGROUND: This study aims to detect alterations in the spatio-chromatic pseudophakic vision produced by multifocal diffractive intraocular lenses (IOLs) and provides a physical interpretation. METHODS: In vitro characterization of the imaging performance of two diffractive IOLs: AT LISA Tri (Zeiss...

Descripción completa

Detalles Bibliográficos
Autores principales: Millan, Maria S., Clavé, Laura, Torrents, Aurora, Armengol, Jesús, Vega, Fidel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391998/
https://www.ncbi.nlm.nih.gov/pubmed/37525263
http://dx.doi.org/10.1186/s40662-023-00350-5
_version_ 1785082850730573824
author Millan, Maria S.
Clavé, Laura
Torrents, Aurora
Armengol, Jesús
Vega, Fidel
author_facet Millan, Maria S.
Clavé, Laura
Torrents, Aurora
Armengol, Jesús
Vega, Fidel
author_sort Millan, Maria S.
collection PubMed
description BACKGROUND: This study aims to detect alterations in the spatio-chromatic pseudophakic vision produced by multifocal diffractive intraocular lenses (IOLs) and provides a physical interpretation. METHODS: In vitro characterization of the imaging performance of two diffractive IOLs: AT LISA Tri (Zeiss) and FineVision (PhysIOL) in on-bench model eye illuminated with red (R, 625 nm), green (G, 530 nm) and blue (B, 455 nm) lights. We used the metrics: energy efficiency (EE), area under the modulation transfer function, longitudinal chromatic aberration (LCA), and halo intensity. Through-focus (TF) analysis and calculation of the expected defocus curve under white (W) daylight were included. In vivo visual acuity (VA) of 50 pseudophakics (60 eyes) was assessed under W, R, G, B lights at far and near. Two clinical experiments evaluated LCA and R, G, B TF-EE effects on pseudophakic vision and their relative importance. RESULTS: Clinical mean VA values under W light agreed with the predicted values at far and near for both IOLs. LCA measurements and R, G, B TF-EE curves were consistent with their lens design based on the 0th and 1st diffraction orders operative for far and near vision, respectively. LCA effects were compensated at near but noticed at far (− 0.75 D under B light). We detected strong asymmetry in visual resolution depending on the object distance and the illuminating wavelength—red predominance at far, blue predominance at near—in consistency with the TF-EE measurements. CONCLUSIONS: Diffractive multifocal IOL designs produce asymmetries in the spatio-chromatic vision of pseudophakics beyond the alterations strictly due to LCA. VA asymmetry for far/near object distance under R and B illumination is clinically detectable in subjects implanted with IOLs with 0th and 1st diffraction orders for far and near vision, respectively. Such VA asymmetry cannot be explained solely from the influence of defocus, as would be derived from a chromatic difference of power, but mainly from the wavelength dependence of the EE. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40662-023-00350-5.
format Online
Article
Text
id pubmed-10391998
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-103919982023-08-02 Spatio-chromatic vision with multifocal diffractive intraocular lens Millan, Maria S. Clavé, Laura Torrents, Aurora Armengol, Jesús Vega, Fidel Eye Vis (Lond) Research BACKGROUND: This study aims to detect alterations in the spatio-chromatic pseudophakic vision produced by multifocal diffractive intraocular lenses (IOLs) and provides a physical interpretation. METHODS: In vitro characterization of the imaging performance of two diffractive IOLs: AT LISA Tri (Zeiss) and FineVision (PhysIOL) in on-bench model eye illuminated with red (R, 625 nm), green (G, 530 nm) and blue (B, 455 nm) lights. We used the metrics: energy efficiency (EE), area under the modulation transfer function, longitudinal chromatic aberration (LCA), and halo intensity. Through-focus (TF) analysis and calculation of the expected defocus curve under white (W) daylight were included. In vivo visual acuity (VA) of 50 pseudophakics (60 eyes) was assessed under W, R, G, B lights at far and near. Two clinical experiments evaluated LCA and R, G, B TF-EE effects on pseudophakic vision and their relative importance. RESULTS: Clinical mean VA values under W light agreed with the predicted values at far and near for both IOLs. LCA measurements and R, G, B TF-EE curves were consistent with their lens design based on the 0th and 1st diffraction orders operative for far and near vision, respectively. LCA effects were compensated at near but noticed at far (− 0.75 D under B light). We detected strong asymmetry in visual resolution depending on the object distance and the illuminating wavelength—red predominance at far, blue predominance at near—in consistency with the TF-EE measurements. CONCLUSIONS: Diffractive multifocal IOL designs produce asymmetries in the spatio-chromatic vision of pseudophakics beyond the alterations strictly due to LCA. VA asymmetry for far/near object distance under R and B illumination is clinically detectable in subjects implanted with IOLs with 0th and 1st diffraction orders for far and near vision, respectively. Such VA asymmetry cannot be explained solely from the influence of defocus, as would be derived from a chromatic difference of power, but mainly from the wavelength dependence of the EE. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40662-023-00350-5. BioMed Central 2023-08-01 /pmc/articles/PMC10391998/ /pubmed/37525263 http://dx.doi.org/10.1186/s40662-023-00350-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Millan, Maria S.
Clavé, Laura
Torrents, Aurora
Armengol, Jesús
Vega, Fidel
Spatio-chromatic vision with multifocal diffractive intraocular lens
title Spatio-chromatic vision with multifocal diffractive intraocular lens
title_full Spatio-chromatic vision with multifocal diffractive intraocular lens
title_fullStr Spatio-chromatic vision with multifocal diffractive intraocular lens
title_full_unstemmed Spatio-chromatic vision with multifocal diffractive intraocular lens
title_short Spatio-chromatic vision with multifocal diffractive intraocular lens
title_sort spatio-chromatic vision with multifocal diffractive intraocular lens
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10391998/
https://www.ncbi.nlm.nih.gov/pubmed/37525263
http://dx.doi.org/10.1186/s40662-023-00350-5
work_keys_str_mv AT millanmarias spatiochromaticvisionwithmultifocaldiffractiveintraocularlens
AT clavelaura spatiochromaticvisionwithmultifocaldiffractiveintraocularlens
AT torrentsaurora spatiochromaticvisionwithmultifocaldiffractiveintraocularlens
AT armengoljesus spatiochromaticvisionwithmultifocaldiffractiveintraocularlens
AT vegafidel spatiochromaticvisionwithmultifocaldiffractiveintraocularlens