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ATP-P2X(7)R-mediated microglia senescence aggravates retinal ganglion cell injury in chronic ocular hypertension

BACKGROUND: Dysfunction of microglia during aging affects normal neuronal function and results in the occurrence of neurodegenerative diseases. Retinal microglial senescence attributes to retinal ganglion cell (RGC) death in glaucoma. This study aims to examine the role of ATP-P2X(7)R in the mediati...

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Detalles Bibliográficos
Autores principales:	Wei, Miao, Zhang, Guowei, Huang, Zeyu, Ding, Xuemeng, Sun, Qing, Zhang, Yujian, Zhu, Rongrong, Guan, Huaijin, Ji, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392012/ https://www.ncbi.nlm.nih.gov/pubmed/37525172 http://dx.doi.org/10.1186/s12974-023-02855-1

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