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ATP-P2X(7)R-mediated microglia senescence aggravates retinal ganglion cell injury in chronic ocular hypertension
BACKGROUND: Dysfunction of microglia during aging affects normal neuronal function and results in the occurrence of neurodegenerative diseases. Retinal microglial senescence attributes to retinal ganglion cell (RGC) death in glaucoma. This study aims to examine the role of ATP-P2X(7)R in the mediati...
Autores principales: | Wei, Miao, Zhang, Guowei, Huang, Zeyu, Ding, Xuemeng, Sun, Qing, Zhang, Yujian, Zhu, Rongrong, Guan, Huaijin, Ji, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392012/ https://www.ncbi.nlm.nih.gov/pubmed/37525172 http://dx.doi.org/10.1186/s12974-023-02855-1 |
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