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IFNγ induces Bcl3 expression by JAK1/STAT1/p65 signaling, resulting in increased IL‐8 expression in ovarian cancer cells

We have recently shown that IFNγ, produced during cancer therapy, induces expression of the Bcl3 proto‐oncogene in ovarian cancer (OC) cells, resulting in their increased proliferation, migration, and invasion, but the mechanisms are unknown. Here, we demonstrate that the IFNγ‐induced Bcl3 expressio...

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Detalles Bibliográficos
Autores principales: Gaire, Bijaya, Padmanabhan, Sveta, Zou, Yue, Uddin, Mohammad M., Reddy, Suprataptha U., Vancurova, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392061/
https://www.ncbi.nlm.nih.gov/pubmed/37151134
http://dx.doi.org/10.1002/2211-5463.13624