Relevance of Coding Variation in FLG And DOCK8 in Finnish Pediatric Patients with Early-Onset Moderate-To-Severe Atopic Dermatitis

Early-onset, persistent atopic dermatitis (AD) is proposed as a distinct subgroup that may have specific genotypic features. FLG gene loss-of-function variants are the best known genetic factors contributing to epidermal barrier impairment and eczema severity. In a cohort of 140 Finnish children wit...

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Detalles Bibliográficos
Autores principales: Perälä, Miia, Kaustio, Meri, Salava, Alexander, Jakkula, Eveliina, Pelkonen, Anna S., Saarela, Janna, Remitz, Anita, Mäkelä, Mika J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392095/
https://www.ncbi.nlm.nih.gov/pubmed/37533579
http://dx.doi.org/10.1016/j.xjidi.2023.100203

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