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Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling

Somatosensory information is processed by a complex network of interneurons in the spinal dorsal horn. It has been reported that inhibitory interneurons that express neuropeptide Y (NPY), either permanently or during development, suppress mechanical itch, with no effect on pain. Here, we investigate...

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Detalles Bibliográficos
Autores principales: Boyle, Kieran A, Polgar, Erika, Gutierrez-Mecinas, Maria, Dickie, Allen C, Cooper, Andrew H, Bell, Andrew M, Jumolea, Evelline, Casas-Benito, Adrian, Watanabe, Masahiko, Hughes, David I, Weir, Gregory A, Riddell, John S, Todd, Andrew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392120/
https://www.ncbi.nlm.nih.gov/pubmed/37490401
http://dx.doi.org/10.7554/eLife.86633