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Prmt5 promotes ciliated cell specification of airway epithelial progenitors via transcriptional inhibition of Tp63

The epithelium of the pulmonary airway is composed of several distinct cell types that differentiate from common progenitor cells to provide defense against environmental insults. Epigenetic mechanisms regulating lineage differentiation of airway epithelial progenitors remain poorly understood. Prot...

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Detalles Bibliográficos
Autores principales: Li, Qiuling, Jiao, Jie, Heng, Ya, Lu, Qingshuang, Zheng, Yu, Li, Huijun, Cai, Jun, Mei, Mei, Bao, Shilai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392137/
https://www.ncbi.nlm.nih.gov/pubmed/37364687
http://dx.doi.org/10.1016/j.jbc.2023.104964

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