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Paper 34: Midterm Outcomes of Meniscal Allograft Transplantation in the Adolescent Population

OBJECTIVES: To report midterm outcomes following primary meniscal allograft transplantation (MAT) from a single surgeon in an adolescent population. METHODS: A retrospective review was performed to identify adolescent patients <18 years old at the time of primary MAT from 1999-2016. International...

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Autores principales: Kaiser, Joshua, Wagner, Kyle, Hevesi, Mario, Damodar, Dhanur, Swindell, Hasani, Yanke, Adam, Cole, Brian, Quigley, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392305/
http://dx.doi.org/10.1177/2325967123S00060
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author Kaiser, Joshua
Wagner, Kyle
Hevesi, Mario
Damodar, Dhanur
Swindell, Hasani
Yanke, Adam
Cole, Brian
Quigley, Ryan
author_facet Kaiser, Joshua
Wagner, Kyle
Hevesi, Mario
Damodar, Dhanur
Swindell, Hasani
Yanke, Adam
Cole, Brian
Quigley, Ryan
author_sort Kaiser, Joshua
collection PubMed
description OBJECTIVES: To report midterm outcomes following primary meniscal allograft transplantation (MAT) from a single surgeon in an adolescent population. METHODS: A retrospective review was performed to identify adolescent patients <18 years old at the time of primary MAT from 1999-2016. International Knee Documentation Committee (IKDC), Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales, and Lysholm scores were collected preoperatively and at 1-year, 2-years, and a minimum of 5-years follow-up. RESULTS: Forty-four (female n=33; male n=11) of 62 identified patients (71%) met inclusion criteria with a mean follow-up of 9.5 ± 3.8 years (range: 5.0-17.7). Isolated MAT was performed in 27 (61.3%) patients. Common concomitant procedures included osteochondral allograft transplantation (OCA) (n=14, 31.8%), autologous chondrocyte implantation (ACI) (n=8, 18.1%), and anterior cruciate ligament reconstruction (ACLR) (n=6, 13.6%) (Table 1). Eleven patients (25%) required a reoperation an average 5.9 ± 4.5 years (range: 0.8 – 14.0) post-transplant. Three (6.8%) patients met criteria for failure, requiring revision MAT an average of 3.8 ± 1.1 years (range: 2.8-4.9) post-transplant. Graft survivability at 1, 2, 5, and 10 years was 100.0%, 100.0%, 93.2%, and 93.2%, respectively (Figure 1). When compared to preoperative scores, significant increases in Lysholm, IKDC, and KOOS subscales were observed at 1-year, 2-year, and most recent follow-up (Figure 2 and Supplemental Table 1). 90% of patients reported satisfaction with their current physical status. CONCLUSIONS: At midterm follow-up, primary MAT in the adolescent population resulted in predictable improvements in functional outcomes. These improvements were maintained at an average follow-up of 9.5 years. The meniscal reoperation rate was 25% with a 71.3% probability of being reoperation free at 5 years while graft survivability was 93.2% at 5 years. When compared to extant literature profiling MAT in the adult population, adolescents who undergo MAT demonstrate similar functional outcomes and graft survivability.
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spelling pubmed-103923052023-08-02 Paper 34: Midterm Outcomes of Meniscal Allograft Transplantation in the Adolescent Population Kaiser, Joshua Wagner, Kyle Hevesi, Mario Damodar, Dhanur Swindell, Hasani Yanke, Adam Cole, Brian Quigley, Ryan Orthop J Sports Med Article OBJECTIVES: To report midterm outcomes following primary meniscal allograft transplantation (MAT) from a single surgeon in an adolescent population. METHODS: A retrospective review was performed to identify adolescent patients <18 years old at the time of primary MAT from 1999-2016. International Knee Documentation Committee (IKDC), Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales, and Lysholm scores were collected preoperatively and at 1-year, 2-years, and a minimum of 5-years follow-up. RESULTS: Forty-four (female n=33; male n=11) of 62 identified patients (71%) met inclusion criteria with a mean follow-up of 9.5 ± 3.8 years (range: 5.0-17.7). Isolated MAT was performed in 27 (61.3%) patients. Common concomitant procedures included osteochondral allograft transplantation (OCA) (n=14, 31.8%), autologous chondrocyte implantation (ACI) (n=8, 18.1%), and anterior cruciate ligament reconstruction (ACLR) (n=6, 13.6%) (Table 1). Eleven patients (25%) required a reoperation an average 5.9 ± 4.5 years (range: 0.8 – 14.0) post-transplant. Three (6.8%) patients met criteria for failure, requiring revision MAT an average of 3.8 ± 1.1 years (range: 2.8-4.9) post-transplant. Graft survivability at 1, 2, 5, and 10 years was 100.0%, 100.0%, 93.2%, and 93.2%, respectively (Figure 1). When compared to preoperative scores, significant increases in Lysholm, IKDC, and KOOS subscales were observed at 1-year, 2-year, and most recent follow-up (Figure 2 and Supplemental Table 1). 90% of patients reported satisfaction with their current physical status. CONCLUSIONS: At midterm follow-up, primary MAT in the adolescent population resulted in predictable improvements in functional outcomes. These improvements were maintained at an average follow-up of 9.5 years. The meniscal reoperation rate was 25% with a 71.3% probability of being reoperation free at 5 years while graft survivability was 93.2% at 5 years. When compared to extant literature profiling MAT in the adult population, adolescents who undergo MAT demonstrate similar functional outcomes and graft survivability. SAGE Publications 2023-07-31 /pmc/articles/PMC10392305/ http://dx.doi.org/10.1177/2325967123S00060 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc-nd/4.0/This open-access article is published and distributed under the Creative Commons Attribution - NonCommercial - No Derivatives License (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits the noncommercial use, distribution, and reproduction of the article in any medium, provided the original author and source are credited. You may not alter, transform, or build upon this article without the permission of the Author(s). For article reuse guidelines, please visit SAGE’s website at http://www.sagepub.com/journals-permissions.
spellingShingle Article
Kaiser, Joshua
Wagner, Kyle
Hevesi, Mario
Damodar, Dhanur
Swindell, Hasani
Yanke, Adam
Cole, Brian
Quigley, Ryan
Paper 34: Midterm Outcomes of Meniscal Allograft Transplantation in the Adolescent Population
title Paper 34: Midterm Outcomes of Meniscal Allograft Transplantation in the Adolescent Population
title_full Paper 34: Midterm Outcomes of Meniscal Allograft Transplantation in the Adolescent Population
title_fullStr Paper 34: Midterm Outcomes of Meniscal Allograft Transplantation in the Adolescent Population
title_full_unstemmed Paper 34: Midterm Outcomes of Meniscal Allograft Transplantation in the Adolescent Population
title_short Paper 34: Midterm Outcomes of Meniscal Allograft Transplantation in the Adolescent Population
title_sort paper 34: midterm outcomes of meniscal allograft transplantation in the adolescent population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392305/
http://dx.doi.org/10.1177/2325967123S00060
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