Synthesis and anticancer properties of celastrol derivatives involved in the inhibition of VEGF

In this study, fourteen celastrol derivatives (1–14) were synthesised by esterification of celastrol at the 29th position. The in vitro anticancer activity of them was determined by the MTT assay. All the synthetic compounds showed significant antiproliferative activity against six cancer cells, wit...

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Detalles Bibliográficos
Autores principales: Song, Mingxia, Wen, Jiantao, Hua, Yi, Zhu, Yangnv, Xia, Qishan, Guo, Qiaoyue, Luo, Yiqin, Deng, Xianqing, Huang, Yushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392308/
https://www.ncbi.nlm.nih.gov/pubmed/37489072
http://dx.doi.org/10.1080/14756366.2023.2238137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392308/
https://www.ncbi.nlm.nih.gov/pubmed/37489072
http://dx.doi.org/10.1080/14756366.2023.2238137

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