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Synthesis and anticancer properties of celastrol derivatives involved in the inhibition of VEGF
In this study, fourteen celastrol derivatives (1–14) were synthesised by esterification of celastrol at the 29th position. The in vitro anticancer activity of them was determined by the MTT assay. All the synthetic compounds showed significant antiproliferative activity against six cancer cells, wit...
Autores principales: | Song, Mingxia, Wen, Jiantao, Hua, Yi, Zhu, Yangnv, Xia, Qishan, Guo, Qiaoyue, Luo, Yiqin, Deng, Xianqing, Huang, Yushan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392308/ https://www.ncbi.nlm.nih.gov/pubmed/37489072 http://dx.doi.org/10.1080/14756366.2023.2238137 |
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