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Poster 289: Time to Achievement of Clinically Significant Outcomes Following Isolated Arthroscopic Meniscal Repair

OBJECTIVES: To comprehensively define the time required to achieve outcomes (CSOs) after arthroscopic meniscal repair (AMR). The primary outcome was to identify an evidence-based timepoint for functional recovery, including the time needed to attain minimally clinically important difference (MCID) a...

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Autores principales: Gamsarian, Vahram, Krishnan, Aditya, Mirle, Vikranth, Levine, Zachary, Berlinberg, Elyse, Chahla, Jorge, Yanke, Adam, Cole, Brian, Verma, Nikhil, Group, Forsythe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392458/
http://dx.doi.org/10.1177/2325967123S00265
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author Gamsarian, Vahram
Krishnan, Aditya
Mirle, Vikranth
Levine, Zachary
Berlinberg, Elyse
Chahla, Jorge
Yanke, Adam
Cole, Brian
Verma, Nikhil
Group, Forsythe
author_facet Gamsarian, Vahram
Krishnan, Aditya
Mirle, Vikranth
Levine, Zachary
Berlinberg, Elyse
Chahla, Jorge
Yanke, Adam
Cole, Brian
Verma, Nikhil
Group, Forsythe
author_sort Gamsarian, Vahram
collection PubMed
description OBJECTIVES: To comprehensively define the time required to achieve outcomes (CSOs) after arthroscopic meniscal repair (AMR). The primary outcome was to identify an evidence-based timepoint for functional recovery, including the time needed to attain minimally clinically important difference (MCID) and patient acceptable symptomatic state (PASS) for isolated AMR. METHODS: Patients who underwent isolated AMR between 2015 and 2021 were collected. Those with completed preoperative and at least 1 post-operative (6-month, 1 year, and 2 years) Patient-Reported Outcome Measures (PROMs), including International Knee Documentation Committee (IKDC), Patient- Reported Outcomes Measurement Information System Physical Function (PROMIS PF), or Knee Injury and Osteoarthritis Outcome Score (KOOS) were included. Exclusion criteria included patients with significant concomitant ligament procedures, concomitant meniscectomies, or prior ipsilateral knee surgery. MCID and PASS for each PROM were identified from prior literature and utilized as a threshold needed to attain functional recovery. The time needed to achieve CSO was then calculated and plotted using Kaplan-Meier survival analysis. RESULTS: Of the 71 included patients (33.8% female, age: 30±14.9 years), 69 patients had completed IKDC forms, and 41 had completed PROMIS PF forms. Patients attained IDKC achievement rates of 84% for MCID and 68% for PASS, and PROMIS PF achievement rates of 80.5% for MCID and 78% for PASS. Median achievement time across all surveys (IKDC, PROMIS PF, and KOOS) ranged between 5.27 - 5.31 months for MCID, and between 5.21–5.40 months for PASS. Averages for achievement time for MCID ranged from 6.28–8.20 months, and for PASS from 6.42 – 9.51 months, in respective PRO surveys. CONCLUSIONS: The majority of patients (72%) undergoing AMR achieved benefit within 6 months of surgery (overall median: 5.3 months), with diminishing proportions at later timepoints. The timeline for achieving improvement that was established by this study may aid in setting patient expectations and designing future outcome studies involving AMR.
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spelling pubmed-103924582023-08-02 Poster 289: Time to Achievement of Clinically Significant Outcomes Following Isolated Arthroscopic Meniscal Repair Gamsarian, Vahram Krishnan, Aditya Mirle, Vikranth Levine, Zachary Berlinberg, Elyse Chahla, Jorge Yanke, Adam Cole, Brian Verma, Nikhil Group, Forsythe Orthop J Sports Med Article OBJECTIVES: To comprehensively define the time required to achieve outcomes (CSOs) after arthroscopic meniscal repair (AMR). The primary outcome was to identify an evidence-based timepoint for functional recovery, including the time needed to attain minimally clinically important difference (MCID) and patient acceptable symptomatic state (PASS) for isolated AMR. METHODS: Patients who underwent isolated AMR between 2015 and 2021 were collected. Those with completed preoperative and at least 1 post-operative (6-month, 1 year, and 2 years) Patient-Reported Outcome Measures (PROMs), including International Knee Documentation Committee (IKDC), Patient- Reported Outcomes Measurement Information System Physical Function (PROMIS PF), or Knee Injury and Osteoarthritis Outcome Score (KOOS) were included. Exclusion criteria included patients with significant concomitant ligament procedures, concomitant meniscectomies, or prior ipsilateral knee surgery. MCID and PASS for each PROM were identified from prior literature and utilized as a threshold needed to attain functional recovery. The time needed to achieve CSO was then calculated and plotted using Kaplan-Meier survival analysis. RESULTS: Of the 71 included patients (33.8% female, age: 30±14.9 years), 69 patients had completed IKDC forms, and 41 had completed PROMIS PF forms. Patients attained IDKC achievement rates of 84% for MCID and 68% for PASS, and PROMIS PF achievement rates of 80.5% for MCID and 78% for PASS. Median achievement time across all surveys (IKDC, PROMIS PF, and KOOS) ranged between 5.27 - 5.31 months for MCID, and between 5.21–5.40 months for PASS. Averages for achievement time for MCID ranged from 6.28–8.20 months, and for PASS from 6.42 – 9.51 months, in respective PRO surveys. CONCLUSIONS: The majority of patients (72%) undergoing AMR achieved benefit within 6 months of surgery (overall median: 5.3 months), with diminishing proportions at later timepoints. The timeline for achieving improvement that was established by this study may aid in setting patient expectations and designing future outcome studies involving AMR. SAGE Publications 2023-07-31 /pmc/articles/PMC10392458/ http://dx.doi.org/10.1177/2325967123S00265 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc-nd/4.0/This open-access article is published and distributed under the Creative Commons Attribution - NonCommercial - No Derivatives License (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits the noncommercial use, distribution, and reproduction of the article in any medium, provided the original author and source are credited. You may not alter, transform, or build upon this article without the permission of the Author(s). For article reuse guidelines, please visit SAGE’s website at http://www.sagepub.com/journals-permissions.
spellingShingle Article
Gamsarian, Vahram
Krishnan, Aditya
Mirle, Vikranth
Levine, Zachary
Berlinberg, Elyse
Chahla, Jorge
Yanke, Adam
Cole, Brian
Verma, Nikhil
Group, Forsythe
Poster 289: Time to Achievement of Clinically Significant Outcomes Following Isolated Arthroscopic Meniscal Repair
title Poster 289: Time to Achievement of Clinically Significant Outcomes Following Isolated Arthroscopic Meniscal Repair
title_full Poster 289: Time to Achievement of Clinically Significant Outcomes Following Isolated Arthroscopic Meniscal Repair
title_fullStr Poster 289: Time to Achievement of Clinically Significant Outcomes Following Isolated Arthroscopic Meniscal Repair
title_full_unstemmed Poster 289: Time to Achievement of Clinically Significant Outcomes Following Isolated Arthroscopic Meniscal Repair
title_short Poster 289: Time to Achievement of Clinically Significant Outcomes Following Isolated Arthroscopic Meniscal Repair
title_sort poster 289: time to achievement of clinically significant outcomes following isolated arthroscopic meniscal repair
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392458/
http://dx.doi.org/10.1177/2325967123S00265
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