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Targeting calcium regulators as therapy for heart failure: focus on the sarcoplasmic reticulum Ca-ATPase pump
Impaired myocardial Ca(2+) cycling is a critical contributor to the development of heart failure (HF), causing changes in the contractile function and structure remodeling of the heart. Within cardiomyocytes, the regulation of sarcoplasmic reticulum (SR) Ca(2+) storage and release is largely depende...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392702/ https://www.ncbi.nlm.nih.gov/pubmed/37534277 http://dx.doi.org/10.3389/fcvm.2023.1185261 |