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Targeting calcium regulators as therapy for heart failure: focus on the sarcoplasmic reticulum Ca-ATPase pump

Impaired myocardial Ca(2+) cycling is a critical contributor to the development of heart failure (HF), causing changes in the contractile function and structure remodeling of the heart. Within cardiomyocytes, the regulation of sarcoplasmic reticulum (SR) Ca(2+) storage and release is largely depende...

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Detalles Bibliográficos
Autor principal: Kho, Changwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392702/
https://www.ncbi.nlm.nih.gov/pubmed/37534277
http://dx.doi.org/10.3389/fcvm.2023.1185261