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Application of biomaterials and nanotechnology in corneal tissue engineering
Corneal diseases are among the most common causes of blindness worldwide. Regardless of the etiology, corneal opacity- or globe integrity-threatening conditions may necessitate corneal replacement procedures. Several procedure types are currently available to address these issues, based on the compl...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392709/ https://www.ncbi.nlm.nih.gov/pubmed/37523589 http://dx.doi.org/10.1177/03000605231190473 |
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author | Soleimani, Mohammad Ebrahimi, Zohreh Ebrahimi, Kosar Sadat Farhadian, Negin Shahlaei, Mohsen Cheraqpour, Kasra Ghasemi, Hamed Moradi, Sajad Chang, Arthur Y. Sharifi, Sina Baharnoori, Seyed Mahbod Djalilian, Ali R. |
author_facet | Soleimani, Mohammad Ebrahimi, Zohreh Ebrahimi, Kosar Sadat Farhadian, Negin Shahlaei, Mohsen Cheraqpour, Kasra Ghasemi, Hamed Moradi, Sajad Chang, Arthur Y. Sharifi, Sina Baharnoori, Seyed Mahbod Djalilian, Ali R. |
author_sort | Soleimani, Mohammad |
collection | PubMed |
description | Corneal diseases are among the most common causes of blindness worldwide. Regardless of the etiology, corneal opacity- or globe integrity-threatening conditions may necessitate corneal replacement procedures. Several procedure types are currently available to address these issues, based on the complexity and extent of injury. Corneal allograft or keratoplasty is considered to be first-line treatment in many cases. However, a significant proportion of the world’s population are reported to have no access to this option due to limitations in donor preparation. Thus, providing an appropriate, safe, and efficient synthetic implant (e.g., artificial cornea) may revolutionize this field. Nanotechnology, with its potential applications, has garnered a lot of recent attention in this area, however, there is seemingly a long way to go. This narrative review provides a brief overview of the therapeutic interventions for corneal pathologies, followed by a summary of current biomaterials used in corneal regeneration and a discussion of the nanotechnologies that can aid in the production of superior implants. |
format | Online Article Text |
id | pubmed-10392709 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-103927092023-08-02 Application of biomaterials and nanotechnology in corneal tissue engineering Soleimani, Mohammad Ebrahimi, Zohreh Ebrahimi, Kosar Sadat Farhadian, Negin Shahlaei, Mohsen Cheraqpour, Kasra Ghasemi, Hamed Moradi, Sajad Chang, Arthur Y. Sharifi, Sina Baharnoori, Seyed Mahbod Djalilian, Ali R. J Int Med Res Review Corneal diseases are among the most common causes of blindness worldwide. Regardless of the etiology, corneal opacity- or globe integrity-threatening conditions may necessitate corneal replacement procedures. Several procedure types are currently available to address these issues, based on the complexity and extent of injury. Corneal allograft or keratoplasty is considered to be first-line treatment in many cases. However, a significant proportion of the world’s population are reported to have no access to this option due to limitations in donor preparation. Thus, providing an appropriate, safe, and efficient synthetic implant (e.g., artificial cornea) may revolutionize this field. Nanotechnology, with its potential applications, has garnered a lot of recent attention in this area, however, there is seemingly a long way to go. This narrative review provides a brief overview of the therapeutic interventions for corneal pathologies, followed by a summary of current biomaterials used in corneal regeneration and a discussion of the nanotechnologies that can aid in the production of superior implants. SAGE Publications 2023-07-31 /pmc/articles/PMC10392709/ /pubmed/37523589 http://dx.doi.org/10.1177/03000605231190473 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Review Soleimani, Mohammad Ebrahimi, Zohreh Ebrahimi, Kosar Sadat Farhadian, Negin Shahlaei, Mohsen Cheraqpour, Kasra Ghasemi, Hamed Moradi, Sajad Chang, Arthur Y. Sharifi, Sina Baharnoori, Seyed Mahbod Djalilian, Ali R. Application of biomaterials and nanotechnology in corneal tissue engineering |
title | Application of biomaterials and nanotechnology in corneal tissue engineering |
title_full | Application of biomaterials and nanotechnology in corneal tissue engineering |
title_fullStr | Application of biomaterials and nanotechnology in corneal tissue engineering |
title_full_unstemmed | Application of biomaterials and nanotechnology in corneal tissue engineering |
title_short | Application of biomaterials and nanotechnology in corneal tissue engineering |
title_sort | application of biomaterials and nanotechnology in corneal tissue engineering |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392709/ https://www.ncbi.nlm.nih.gov/pubmed/37523589 http://dx.doi.org/10.1177/03000605231190473 |
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