Oncogenic DNA methyltransferase 1 activates the PI3K/AKT/mTOR signalling by blocking the binding of HSPB8 and BAG3 in melanoma

Abnormal DNA methylation has been observed in multiple malignancies, including melanoma. In this study, we initially noticed the overexpression of DNA methyltransferase 1 (DNMT1) in melanoma samples in bioinformatics analysis and, subsequently, validated it in the purchased melanoma cell lines. Afte...

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Detalles Bibliográficos
Autores principales: Yang, Yemei, Ma, Shengfang, Ye, Zi, Zheng, Yushi, Zheng, Zhenjiong, Liu, Xiongshan, Zhou, Xianyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392740/
https://www.ncbi.nlm.nih.gov/pubmed/37523636
http://dx.doi.org/10.1080/15592294.2023.2239607

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