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Cortical cerebrovascular and metabolic perturbations in the 5xFAD mouse model of Alzheimer’s disease
INTRODUCTION: The 5xFAD mouse is a popular model of familial Alzheimer’s disease (AD) that is characterized by early beta-amyloid (Aβ) deposition and cognitive decrements. Despite numerous studies, the 5xFAD mouse has not been comprehensively phenotyped for vascular and metabolic perturbations over...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392850/ https://www.ncbi.nlm.nih.gov/pubmed/37533765 http://dx.doi.org/10.3389/fnagi.2023.1220036 |