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Cortical cerebrovascular and metabolic perturbations in the 5xFAD mouse model of Alzheimer’s disease

INTRODUCTION: The 5xFAD mouse is a popular model of familial Alzheimer’s disease (AD) that is characterized by early beta-amyloid (Aβ) deposition and cognitive decrements. Despite numerous studies, the 5xFAD mouse has not been comprehensively phenotyped for vascular and metabolic perturbations over...

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Detalles Bibliográficos
Autores principales: Jullienne, Amandine, Szu, Jenny I., Quan, Ryan, Trinh, Michelle V., Norouzi, Tannoz, Noarbe, Brenda P., Bedwell, Amanda A., Eldridge, Kierra, Persohn, Scott C., Territo, Paul R., Obenaus, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392850/
https://www.ncbi.nlm.nih.gov/pubmed/37533765
http://dx.doi.org/10.3389/fnagi.2023.1220036

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