Cargando…
Cortical cerebrovascular and metabolic perturbations in the 5xFAD mouse model of Alzheimer’s disease
INTRODUCTION: The 5xFAD mouse is a popular model of familial Alzheimer’s disease (AD) that is characterized by early beta-amyloid (Aβ) deposition and cognitive decrements. Despite numerous studies, the 5xFAD mouse has not been comprehensively phenotyped for vascular and metabolic perturbations over...
Autores principales: | Jullienne, Amandine, Szu, Jenny I., Quan, Ryan, Trinh, Michelle V., Norouzi, Tannoz, Noarbe, Brenda P., Bedwell, Amanda A., Eldridge, Kierra, Persohn, Scott C., Territo, Paul R., Obenaus, Andre |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392850/ https://www.ncbi.nlm.nih.gov/pubmed/37533765 http://dx.doi.org/10.3389/fnagi.2023.1220036 |
Ejemplares similares
-
Prophylactic evaluation of verubecestat on disease‐ and symptom‐modifying effects in 5XFAD mice
por: Oblak, Adrian L., et al.
Publicado: (2022) -
Progressive Vascular Abnormalities in the Aging 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Jullienne, Amandine, et al.
Publicado: (2022) -
Neuroimaging of Mouse Models of Alzheimer’s Disease
por: Jullienne, Amandine, et al.
Publicado: (2022) -
Selective Regional Loss of Cortical Synapses Lacking Presynaptic Mitochondria in the 5xFAD Mouse Model
por: Seo, Na-young, et al.
Publicado: (2021) -
Maternal Undernutrition Modulates Neonatal Rat Cerebrovascular Structure, Function, and Vulnerability to Mild Hypoxic-Ischemic Injury via Corticosteroid-Dependent and -Independent Mechanisms
por: Franco, Patsy Naomi, et al.
Publicado: (2021)