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C–C bond formation via photocatalytic direct functionalization of simple alkanes
The direct functionalization of alkanes represents a very important challenge in the goal to develop more atom-efficient and clean C–C bond forming reactions. These processes, however, are hampered by the low reactivity of the aliphatic C–H bonds. Photocatalytic processes based on hydrogen atom tran...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392964/ https://www.ncbi.nlm.nih.gov/pubmed/37417212 http://dx.doi.org/10.1039/d3cc02790b |
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author | Velasco-Rubio, Álvaro Martínez-Balart, Pol Álvarez-Constantino, Andrés M. Fañanás-Mastral, Martín |
author_facet | Velasco-Rubio, Álvaro Martínez-Balart, Pol Álvarez-Constantino, Andrés M. Fañanás-Mastral, Martín |
author_sort | Velasco-Rubio, Álvaro |
collection | PubMed |
description | The direct functionalization of alkanes represents a very important challenge in the goal to develop more atom-efficient and clean C–C bond forming reactions. These processes, however, are hampered by the low reactivity of the aliphatic C–H bonds. Photocatalytic processes based on hydrogen atom transfer C–H bond activation strategies have become a useful tool to activate and functionalize these inert compounds. In this article, we summarize the main achievements in this field applied to the development of C–C bond forming reactions, and we discuss the key mechanistic features that enable these transformations. |
format | Online Article Text |
id | pubmed-10392964 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-103929642023-08-02 C–C bond formation via photocatalytic direct functionalization of simple alkanes Velasco-Rubio, Álvaro Martínez-Balart, Pol Álvarez-Constantino, Andrés M. Fañanás-Mastral, Martín Chem Commun (Camb) Chemistry The direct functionalization of alkanes represents a very important challenge in the goal to develop more atom-efficient and clean C–C bond forming reactions. These processes, however, are hampered by the low reactivity of the aliphatic C–H bonds. Photocatalytic processes based on hydrogen atom transfer C–H bond activation strategies have become a useful tool to activate and functionalize these inert compounds. In this article, we summarize the main achievements in this field applied to the development of C–C bond forming reactions, and we discuss the key mechanistic features that enable these transformations. The Royal Society of Chemistry 2023-06-29 /pmc/articles/PMC10392964/ /pubmed/37417212 http://dx.doi.org/10.1039/d3cc02790b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Velasco-Rubio, Álvaro Martínez-Balart, Pol Álvarez-Constantino, Andrés M. Fañanás-Mastral, Martín C–C bond formation via photocatalytic direct functionalization of simple alkanes |
title | C–C bond formation via photocatalytic direct functionalization of simple alkanes |
title_full | C–C bond formation via photocatalytic direct functionalization of simple alkanes |
title_fullStr | C–C bond formation via photocatalytic direct functionalization of simple alkanes |
title_full_unstemmed | C–C bond formation via photocatalytic direct functionalization of simple alkanes |
title_short | C–C bond formation via photocatalytic direct functionalization of simple alkanes |
title_sort | c–c bond formation via photocatalytic direct functionalization of simple alkanes |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392964/ https://www.ncbi.nlm.nih.gov/pubmed/37417212 http://dx.doi.org/10.1039/d3cc02790b |
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