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C–C bond formation via photocatalytic direct functionalization of simple alkanes

The direct functionalization of alkanes represents a very important challenge in the goal to develop more atom-efficient and clean C–C bond forming reactions. These processes, however, are hampered by the low reactivity of the aliphatic C–H bonds. Photocatalytic processes based on hydrogen atom tran...

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Detalles Bibliográficos
Autores principales: Velasco-Rubio, Álvaro, Martínez-Balart, Pol, Álvarez-Constantino, Andrés M., Fañanás-Mastral, Martín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392964/
https://www.ncbi.nlm.nih.gov/pubmed/37417212
http://dx.doi.org/10.1039/d3cc02790b
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author Velasco-Rubio, Álvaro
Martínez-Balart, Pol
Álvarez-Constantino, Andrés M.
Fañanás-Mastral, Martín
author_facet Velasco-Rubio, Álvaro
Martínez-Balart, Pol
Álvarez-Constantino, Andrés M.
Fañanás-Mastral, Martín
author_sort Velasco-Rubio, Álvaro
collection PubMed
description The direct functionalization of alkanes represents a very important challenge in the goal to develop more atom-efficient and clean C–C bond forming reactions. These processes, however, are hampered by the low reactivity of the aliphatic C–H bonds. Photocatalytic processes based on hydrogen atom transfer C–H bond activation strategies have become a useful tool to activate and functionalize these inert compounds. In this article, we summarize the main achievements in this field applied to the development of C–C bond forming reactions, and we discuss the key mechanistic features that enable these transformations.
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spelling pubmed-103929642023-08-02 C–C bond formation via photocatalytic direct functionalization of simple alkanes Velasco-Rubio, Álvaro Martínez-Balart, Pol Álvarez-Constantino, Andrés M. Fañanás-Mastral, Martín Chem Commun (Camb) Chemistry The direct functionalization of alkanes represents a very important challenge in the goal to develop more atom-efficient and clean C–C bond forming reactions. These processes, however, are hampered by the low reactivity of the aliphatic C–H bonds. Photocatalytic processes based on hydrogen atom transfer C–H bond activation strategies have become a useful tool to activate and functionalize these inert compounds. In this article, we summarize the main achievements in this field applied to the development of C–C bond forming reactions, and we discuss the key mechanistic features that enable these transformations. The Royal Society of Chemistry 2023-06-29 /pmc/articles/PMC10392964/ /pubmed/37417212 http://dx.doi.org/10.1039/d3cc02790b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Velasco-Rubio, Álvaro
Martínez-Balart, Pol
Álvarez-Constantino, Andrés M.
Fañanás-Mastral, Martín
C–C bond formation via photocatalytic direct functionalization of simple alkanes
title C–C bond formation via photocatalytic direct functionalization of simple alkanes
title_full C–C bond formation via photocatalytic direct functionalization of simple alkanes
title_fullStr C–C bond formation via photocatalytic direct functionalization of simple alkanes
title_full_unstemmed C–C bond formation via photocatalytic direct functionalization of simple alkanes
title_short C–C bond formation via photocatalytic direct functionalization of simple alkanes
title_sort c–c bond formation via photocatalytic direct functionalization of simple alkanes
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10392964/
https://www.ncbi.nlm.nih.gov/pubmed/37417212
http://dx.doi.org/10.1039/d3cc02790b
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