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Cationic proteins from eosinophils bind bone morphogenetic protein receptors promoting vascular calcification and atherogenesis

AIMS: Blood eosinophil count and eosinophil cationic protein (ECP) concentration are risk factors of cardiovascular diseases. This study tested whether and how eosinophils and ECP contribute to vascular calcification and atherogenesis. METHODS AND RESULTS: Immunostaining revealed eosinophil accumula...

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Detalles Bibliográficos
Autores principales: Meng, Zhaojie, Zhang, Shuya, Li, Wei, Wang, Yunzhe, Wang, Minjie, Liu, Xin, Liu, Cong-Lin, Liao, Sha, Liu, Tianxiao, Yang, Chongzhe, Lindholt, Jes S, Rasmussen, Lars M, Obel, Lasse M, Stubbe, Jane, Diederichsen, Axel C, Sun, Yong, Chen, Yabing, Yu, Paul B, Libby, Peter, Shi, Guo-Ping, Guo, Junli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393071/
https://www.ncbi.nlm.nih.gov/pubmed/37279475
http://dx.doi.org/10.1093/eurheartj/ehad262