Sirtuin 2 deficiency aggravates ageing-induced vascular remodelling in humans and mice

AIMS: The mechanisms underlying ageing-induced vascular remodelling remain unclear. This study investigates the role and underlying mechanisms of the cytoplasmic deacetylase sirtuin 2 (SIRT2) in ageing-induced vascular remodelling. METHODS AND RESULTS: Transcriptome and quantitative real-time PCR da...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Wang, Xiaoman, Li, Xun-Kai, Lv, Shuang-Jie, Wang, He-Ping, Liu, Yang, Zhou, Jingyue, Gong, Hui, Chen, Xiao-Feng, Ren, Si-Chong, Zhang, Huina, Dai, Yuxiang, Cai, Hua, Yan, Bo, Chen, Hou-Zao, Tang, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393077/
https://www.ncbi.nlm.nih.gov/pubmed/37377116
http://dx.doi.org/10.1093/eurheartj/ehad381

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