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Structure and DNA-bridging activity of the essential Rec114–Mei4 trimer interface

The DNA double-strand breaks (DSBs) that initiate meiotic recombination are formed by an evolutionarily conserved suite of factors that includes Rec114 and Mei4 (RM), which regulate DSB formation both spatially and temporally. In vivo, these proteins form large immunostaining foci that are integrate...

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Detalles Bibliográficos
Autores principales: Liu, Kaixian, Grasso, Emily M., Pu, Stephen, Zou, Mengyang, Liu, Shixin, Eliezer, David, Keeney, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393192/
https://www.ncbi.nlm.nih.gov/pubmed/37442580
http://dx.doi.org/10.1101/gad.350461.123