Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain

The consolidation of unambiguous cell fate commitment relies on the ability of transcription factors (TFs) to exert tissue-specific regulation of complex genetic networks. However, the mechanisms by which TFs establish such precise control over gene expression have remained elusive—especially in ins...

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Detalles Bibliográficos
Autores principales: Abarinov, Vladimir, Levine, Joshua A., Churchill, Angela J., Hopwood, Bryce, Deiter, Cailin S., Guney, Michelle A., Wells, Kristen L., Schrunk, Jessica M., Guo, Yuchun, Hammelman, Jennifer, Gifford, David K., Magnuson, Mark A., Wichterle, Hynek, Sussel, Lori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393193/
https://www.ncbi.nlm.nih.gov/pubmed/37364986
http://dx.doi.org/10.1101/gad.350569.123

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