REST contributes to AKI-to-CKD transition through inducing ferroptosis in renal tubular epithelial cells

Ischemic-reperfusion injury (IRI) is a major pathogenic factor in acute kidney injury (AKI), which directly leads to the hypoxic injury of renal tubular epithelial cells (RTECs). Although emerging studies suggest repressor element 1–silencing transcription factor (REST) as a master regulator of gene...

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Detalles Bibliográficos
Autores principales: Gong, Shuiqin, Zhang, Aihong, Yao, Mengying, Xin, Wang, Guan, Xu, Qin, Shaozong, Liu, Yong, Xiong, Jiachuan, Yang, Ke, Xiong, Li, He, Ting, Huang, Yinghui, Zhao, Jinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393228/
https://www.ncbi.nlm.nih.gov/pubmed/37288660
http://dx.doi.org/10.1172/jci.insight.166001

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