Single-cell landscape analysis unravels molecular programming of the human B cell compartment in chronic GVHD

Alloreactivity can drive autoimmune syndromes. After allogeneic hematopoietic stem cell transplantation (allo-HCT), chronic graft-versus-host disease (cGVHD), a B cell–associated autoimmune-like syndrome, commonly occurs. Because donor-derived B cells continually develop under selective pressure fro...

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Detalles Bibliográficos
Autores principales: Poe, Jonathan C., Fang, Jiyuan, Zhang, Dadong, Lee, Marissa R., DiCioccio, Rachel A., Su, Hsuan, Qin, Xiaodi, Zhang, Jennifer Y., Visentin, Jonathan, Bracken, Sonali J., Ho, Vincent T., Wang, Kathy S., Rose, Jeremy J., Pavletic, Steven Z., Hakim, Frances T., Jia, Wei, Suthers, Amy N., Curry-Chisolm, Itaevia M., Horwitz, Mitchell E., Rizzieri, David A., McManigle, William C., Chao, Nelson J., Cardones, Adela R., Xie, Jichun, Owzar, Kouros, Sarantopoulos, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393230/
https://www.ncbi.nlm.nih.gov/pubmed/37129971
http://dx.doi.org/10.1172/jci.insight.169732

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