Cargando…

PRDM16 deficiency in vascular smooth muscle cells aggravates abdominal aortic aneurysm

Abdominal aortic aneurysm (AAA) is usually asymptomatic until life-threatening complications occur, predominantly involving aortic rupture. Currently, no drug-based treatments are available, primarily due to limited understanding of AAA pathogenesis. The transcriptional regulator PR domain–containin...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zhenguo, Zhao, Xiangjie, Zhao, Guizhen, Guo, Yanhong, Lu, Haocheng, Mu, Wenjuan, Zhong, Juan, Garcia-Barrio, Minerva, Zhang, Jifeng, Chen, Y. Eugene, Chang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393233/
https://www.ncbi.nlm.nih.gov/pubmed/37079380
http://dx.doi.org/10.1172/jci.insight.167041