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PRDM16 deficiency in vascular smooth muscle cells aggravates abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA) is usually asymptomatic until life-threatening complications occur, predominantly involving aortic rupture. Currently, no drug-based treatments are available, primarily due to limited understanding of AAA pathogenesis. The transcriptional regulator PR domain–containin...
Autores principales: | Wang, Zhenguo, Zhao, Xiangjie, Zhao, Guizhen, Guo, Yanhong, Lu, Haocheng, Mu, Wenjuan, Zhong, Juan, Garcia-Barrio, Minerva, Zhang, Jifeng, Chen, Y. Eugene, Chang, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393233/ https://www.ncbi.nlm.nih.gov/pubmed/37079380 http://dx.doi.org/10.1172/jci.insight.167041 |
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