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A versatile laser-induced porcine model of outer retinal and choroidal degeneration for preclinical testing

Over 30 million people worldwide suffer from untreatable vision loss and blindness associated with childhood-onset and age-related eye diseases caused by photoreceptor (PR), retinal pigment epithelium (RPE), and choriocapillaris (CC) degeneration. Recent work suggests that RPE-based cell therapy may...

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Detalles Bibliográficos
Autores principales: Barone, Francesca, Amaral, Juan, Bunea, Irina, Farnoodian, Mitra, Gupta, Rohan, Gupta, Rishabh, Baker, Dara, Phillips, M. Joseph, Blanch, Richard J., Maminishkis, Arvydas, Gamm, David M., Bharti, Kapil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393234/
https://www.ncbi.nlm.nih.gov/pubmed/37288665
http://dx.doi.org/10.1172/jci.insight.157654