MOGAD patient autoantibodies induce complement, phagocytosis, and cellular cytotoxicity

Myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD) is an inflammatory demyelinating CNS condition characterized by the presence of MOG autoantibodies. We sought to investigate whether human MOG autoantibodies are capable of mediating damage to MOG-expressing cells through...

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Detalles Bibliográficos
Autores principales: Yandamuri, Soumya S., Filipek, Beata, Obaid, Abeer H., Lele, Nikhil, Thurman, Joshua M., Makhani, Naila, Nowak, Richard J., Guo, Yong, Lucchinetti, Claudia F., Flanagan, Eoin P., Longbrake, Erin E., O’Connor, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393237/
https://www.ncbi.nlm.nih.gov/pubmed/37097758
http://dx.doi.org/10.1172/jci.insight.165373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393237/
https://www.ncbi.nlm.nih.gov/pubmed/37097758
http://dx.doi.org/10.1172/jci.insight.165373

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