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MOGAD patient autoantibodies induce complement, phagocytosis, and cellular cytotoxicity
Myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD) is an inflammatory demyelinating CNS condition characterized by the presence of MOG autoantibodies. We sought to investigate whether human MOG autoantibodies are capable of mediating damage to MOG-expressing cells through...
Autores principales: | Yandamuri, Soumya S., Filipek, Beata, Obaid, Abeer H., Lele, Nikhil, Thurman, Joshua M., Makhani, Naila, Nowak, Richard J., Guo, Yong, Lucchinetti, Claudia F., Flanagan, Eoin P., Longbrake, Erin E., O’Connor, Kevin C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393237/ https://www.ncbi.nlm.nih.gov/pubmed/37097758 http://dx.doi.org/10.1172/jci.insight.165373 |
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