Cargando…

Hippocampal differential expression underlying the neuroprotective effect of delta-9-tetrahydrocannabinol microdose on old mice

Delta-9-tetrahydrocannabinol (THC) is the primary psychoactive compound of the cannabis plant and an exogenous ligand of the endocannabinoid system. In previous studies, we demonstrated that a single microdose of THC (0.002 mg/kg, 3–4 orders of magnitude lower than the standard dose for rodents) exe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shapira, Guy, Israel-Elgali, Ifat, Grad, Meitar, Avnat, Eden, Rachmany, Lital, Sarne, Yosef, Shomron, Noam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10393280/ https://www.ncbi.nlm.nih.gov/pubmed/37534036 http://dx.doi.org/10.3389/fnins.2023.1182932

Ejemplares similares

Comprehensive Genetic Analysis of Druze Provides Insights into Carrier Screening
por: Avnat, Eden, et al.
Publicado: (2023)

Elevated Expression of RGS2 May Underlie Reduced Olfaction in COVID-19 Patients
por: Avnat, Eden, et al.
Publicado: (2022)

Characterization of MicroRNA and Gene Expression Profiles Following Ricin Intoxication
por: Pillar, Nir, et al.
Publicado: (2019)

Altered White Matter and microRNA Expression in a Murine Model Related to Williams Syndrome Suggests That miR-34b/c Affects Brain Development via Ptpru and Dcx Modulation
por: Grad, Meitar, et al.
Publicado: (2022)

Genome wide analysis implicates upregulation of proteasome pathway in major depressive disorder
por: Belaish, Shaked, et al.
Publicado: (2021)

Transcriptomic Analysis of Human Fragile X Syndrome Neurons Reveals Neurite Outgrowth Modulation by the TGFβ/BMP Pathway
por: Kuznitsov-Yanovsky, Liron, et al.
Publicado: (2022)

Microdeletion of 16q24.1–q24.2—A unique etiology of Lymphedema–Distichiasis syndrome and neurodevelopmental disorder
por: Michelson, Marina, et al.
Publicado: (2022)

Delta-8 Tetrahydrocannabinol Product Impurities
por: Ray, Colleen L., et al.
Publicado: (2022)

Population differences in antibody response to SARS‐CoV‐2 infection and BNT162b2 vaccination
por: Shapira, Guy, et al.
Publicado: (2022)

Delta-9-tetrahydrocannabinol reduces willingness to exert effort in women
por: Wardle, Margaret C., et al.
Publicado: (2022)

Self-Rated Effectiveness of Microdosing With Psychedelics for Mental and Physical Health Problems Among Microdosers
por: Hutten, Nadia R. P. W., et al.
Publicado: (2019)

Acute Effects of Delta-9-Tetrahydrocannabinol on Performance Monitoring in Healthy Volunteers
por: Spronk, Desirée, et al.
Publicado: (2011)

Microdosing: Concept, Application and Relevance
por: Tewari, Tushar, et al.
Publicado: (2010)

Asking questions of psychedelic microdosing
por: Cameron, Lindsay P
Publicado: (2021)

Using Functional Near-Infrared Spectroscopy to Measure Effects of Delta 9-Tetrahydrocannabinol on Prefrontal Activity and Working Memory in Cannabis Users
por: Keles, Hasan O., et al.
Publicado: (2017)

Unexpected gender differences in progressive supranuclear palsy reveal efficacy for davunetide in women
por: Gozes, Illana, et al.
Publicado: (2023)

Immunosuppression as a Hub for SARS-CoV-2 Mutational Drift
por: Shapira, Guy, et al.
Publicado: (2023)

Effect of Delta-9-Tetrahydrocannabinol on Mouse Resistance to Systemic Candida albicans Infection
por: Blumstein, Gideon W., et al.
Publicado: (2014)

Descriptive Psychopathology of the Acute Effects of Intravenous Delta-9-Tetrahydrocannabinol Administration in Humans
por: Colizzi, Marco, et al.
Publicado: (2019)

A Conversion of Oral Cannabidiol to Delta9-Tetrahydrocannabinol Seems Not to Occur in Humans
por: Nahler, Gerhard, et al.
Publicado: (2017)

Glucocorticoids, Stress and Delta-9 Tetrahydrocannabinol (THC) during Early Embryonic Development
por: Kuzma-Hunt, Alexander G., et al.
Publicado: (2021)

Effects of Delta-9 Tetrahydrocannabinol (THC) on Oocyte Competence and Early Embryonic Development
por: Misner, Megan J., et al.
Publicado: (2021)

Transcriptional Alterations Induced by Delta-9 Tetrahydrocannabinol in the Brain and Gonads of Adult Medaka
por: Vassall, Marlee, et al.
Publicado: (2023)

Neuroprotective Effects of Cannabidiol but Not Δ(9)-Tetrahydrocannabinol in Rat Hippocampal Slices Exposed to Oxygen-Glucose Deprivation: Studies with Cannabis Extracts and Selected Cannabinoids
por: Landucci, Elisa, et al.
Publicado: (2021)

An Ultra-Low Dose of ∆9-Tetrahydrocannabinol Alleviates Alzheimer’s Disease-Related Cognitive Impairments and Modulates TrkB Receptor Expression in a 5XFAD Mouse Model
por: Nitzan, Keren, et al.
Publicado: (2022)

MicroRNA-Mediated Regulation of ITGB3 and CHL1 Is Implicated in SSRI Action
por: Oved, Keren, et al.
Publicado: (2017)

A systematic study of microdosing psychedelics
por: Polito, Vince, et al.
Publicado: (2019)

The therapeutic potential of microdosing psychedelics in depression
por: Kuypers, Kim P.C.
Publicado: (2020)

Delta-9 tetrahydrocannabinol (THC) inhibits lytic replication of gamma oncogenic herpesviruses in vitro
por: Medveczky, Maria M, et al.
Publicado: (2004)

Disposable screen printed sensor for the electrochemical detection of delta-9-tetrahydrocannabinol in undiluted saliva
por: Wanklyn, Ceri, et al.
Publicado: (2016)

Delta-9-tetrahydrocannabinol, neural oscillations above 20 Hz and induced acute psychosis
por: Nottage, Judith F., et al.
Publicado: (2014)

Psychoactive drugs and false memory: comparison of dextroamphetamine and delta-9-tetrahydrocannabinol on false recognition
por: Ballard, Michael E., et al.
Publicado: (2011)

Delta-9-tetrahydrocannabinol and cannabidiol: Separating the chemicals from the “weed,” a pharmacodynamic discussion
por: Boggs, Douglas Lee, et al.
Publicado: (2016)

Delta-9-tetrahydrocannabinol increases striatal glutamate levels in healthy individuals: implications for psychosis
por: Colizzi, Marco, et al.
Publicado: (2019)

Antitumor Effects of Delta (9)-Tetrahydrocannabinol and Cannabinol on Cholangiocarcinoma Cells and Xenograft Mouse Models
por: Leelawat, Surang, et al.
Publicado: (2022)

Analgesia by intrathecal delta-9-tetrahydrocannabinol is dependent on Cav3.2 calcium channels
por: Gadotti, Vinicius de Maria, et al.
Publicado: (2023)

Self-reported adverse events associated with ∆(8)-Tetrahydrocannabinol (Delta-8-THC) Use
por: Leas, Eric C., et al.
Publicado: (2023)

Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers
por: Rootman, Joseph M., et al.
Publicado: (2021)

Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month relative to non-microdosing controls
por: Rootman, Joseph M., et al.
Publicado: (2022)

Phase 0 - Microdosing strategy in clinical trials
por: Rani, P. Usha, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_10ielgk1a8tccfdohjph4mqn9a